Search for dissertations about: "C. albicans"

Showing result 1 - 5 of 30 swedish dissertations containing the words C. albicans.

2. 1. Candida albicans adaption to host microenvironments drives immune evasion

   Author : José Pedro Lopes; Constantin F. Urban; Alistair Brown; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fungi; candida albicans; neutrophils; mast cells; immune evasion; mycoses; infectious diseases; immunologi; Immunology; Infectious Diseases; infektionssjukdomar; Molecular Immunology; molekylär immunologi;

   Abstract : Immunosuppressed patients are frequently afflicted with severe mycoses caused by opportunistic fungal pathogens. Besides being a commensal colonizing predominantly skin and mucosal surfaces, Candida albicans is the most common human fungal pathogen. READ MORE

4. 2. Innate immune factors in recurrent and persistent infections of the lower female genital tract

   Author : Cathrin Alvendal; Karolinska Institutet; Karolinska Institutet; []
   Keywords : C. albicans;

   Abstract : Background: Infections of the female genital tract are common and have severe impact on the quality of life and sexual health of affected women. The innate immune system is crucial and is involved in the defense of infections. READ MORE

5. 3. Interaction Studies of Secreted Aspartic Proteases (Saps) from Candida albicans : Application for Drug Discovery

   Author : Dan Backman; Helena Danielson; Birgitta Tomkinson; Gunnar Henriksson; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; SPR Biosensor; Secreted aspartic proteases; Candida albicans; interaction kinetics; drug discovery; protease inhibitor; Biokemi; Biochemistry; Biokemi;

   Abstract : This thesis is focused on enzymatic studies of the secreted aspartic proteases (Saps) from Candida albicans as a tool for discovery of anti-candida drugs. C. albicans causes infections in a number of different locations, which differ widely in the protein substrates available and pH. Since C. READ MORE

6. 4. Pharmaceutical And Immunollogical Challenge Of Fungal Pathogens

   Author : Marios Stylianou; Constantin F. Urban; Christophe d' Enfert; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mast cells; Candida albicans; yeast to hyphal form; antifungal drugs; repurposed drugs; HTS;

   Abstract : Incidences of fungal infections are on the rise in immunosuppressed people. Predominant causative agents for these mycoses are species of the genus Candida, including Candida albicans, Candida glabrata and Candida dublieniensis. Despite a wide range of emerging pathogens, C. albicans remains the leading cause. READ MORE

7. 5. The Role of Proline Catabolism in Candida albicans Pathogenesis

   Author : Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. READ MORE