Search for dissertations about: "C.elegans"

Showing result 1 - 5 of 54 swedish dissertations containing the word C.elegans.

  1. 1. Hyperoxia avoidance and aggregation behavior in C. elegans

    Author : Annelie Persson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; c. elegans; aggregation;

    Abstract : Living in the soil, C. elegans can move in three dimensions in search for food. To navigate, it partly uses oxygen levels as a description of its habitat. Oxygen tension may indicate presence of microbial food and location with respect to the surface, where oxygen is 21%. READ MORE

  2. 2. ASNA1 and cisplatin resistance : studies in C. elegans and in human tumor cells

    Author : Oskar Hemmingsson; Peter Naredi; Mef Nilbert; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ASNA1; Cisplatin; C. elegans; Drug resistance; Apoptosis; Surgery; Kirurgi; Oncology; Onkologi; Surgery; kirurgi; Oncology; onkologi; cellforskning; cell research;

    Abstract : Platinum based chemotherapy is widely used to treat cancer. Cisplatin (diamminedichloroplatinum) combination treatments provide cure for metastatic testicular cancer and prolong survival for patients suffering from ovarian, head and neck, bladder and non small cell lung cancer. READ MORE

  3. 3. Axon Guidance and Morphogenesis of the C. elegans Pharynx

    Author : Manish Rauthan; Chalmers University of Technology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharynx; M2; C. elegans; extra-cellular matrix ECM ; hex; Krüppel; pha-2; isthmus; NSM; pharyngeal neurons.; cytoskeleton; mnm-2;

    Abstract : The C. elegans pharynx is a single cell thick muscular tube that undergoes morphogenesis to attain it mature structure from a ball of 80 undifferentiated cells. This thesis is about understanding the mechanisms and the genetic pathways underlying the process of pharyngeogenesis. READ MORE

  4. 4. Inhibition of the mevalonate pathway in C. elegans: Consequences and implications

    Author : Parmida Ranji; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Mevalonate pathway; C. elegans; atfs-1; mitochondrial unfolded response UPR ;

    Abstract : The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q (a component of the electron transport chain in mitochondria), dolichols (important for N-linked glycosylation of proteins) and isoprenoids (important for the membrane association of small GTPases). This thesis concerns novel findings about the effect of statin on the mevalonate pathway using C. READ MORE

  5. 5. New modifiers of insulin signalling identified by interaction screens with ASNA-1 in C. elegans

    Author : Balasubramanian Natarajan; Peter Naredi; Richard Padgett; Umeå universitet; []
    Keywords : Insulin; C. elegans; ASNA1; Cisplatin; GRP94; unfolded protein response; SMN1; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Abstract : Background: Insulin is a hormone released by the pancreatic beta cells in response to elevated levels of nutrients in the blood. Insulin triggers the uptake of glucose, fatty acids and amino acids into the liver, adipose tissue and muscles. READ MORE