Search for dissertations about: "C4b-binding protein"

Showing result 1 - 5 of 21 swedish dissertations containing the words C4b-binding protein.

  1. 1. Structural and functional studies of C4b-binding protein (C4BP)

    University dissertation from Lena Kask, Wallenberg Laboratory, floor 6, entrance 46, UMAS, S-205 02 Malmö

    Author : Lena Kask; Lund University.; Lunds universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phagocytosis; apoptosis; protein S; complement control protein CCP domains; factor H fH ; Complement; C4b-binding protein C4BP ; intracellular assembly; Clinical chemistry; Klinisk kemi;

    Abstract : The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. READ MORE

  2. 2. C4b-binding protein : studies on its interactions with C4b, protein S and serum amyloid P component

    University dissertation from Department of Clinical Chemistry, Lund University

    Author : Ylva Härdig; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; coagulation system; complement system; serum amyloid P component; C4b; C4b-binding protein; protein S; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : C4b-binding protein (C4BP) is an acute-phase plasma glycoprotein which regulates the complement system through its affinity for C4b. In addition, C4BP binds to the anticoagulant protein S and to serum amyloid P component (SAP). Protein S is a vitamin K-dependent protein which looses its anticoagulant properties when binding to C4BP. READ MORE

  3. 3. Interactions between Streptococcus pyogenes and the human immune system, with special reference to C4b-binding protein

    University dissertation from Medical Microbiology, Lund University

    Author : Anette Thern; Lund University.; Lunds universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Phagocytosis; M-proteins; M-like proteins; Bovine C4b-binding protein; Streptococcus pyogenes; Human C4b-binding protein; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. READ MORE

  4. 4. C4b-binding protein: Identification of binding sites and a possible function of the interaction with protein S

    University dissertation from Joanna Webb, Wallenberg Laboratory Floor 6, U-MAS, S-205 02 Malmö, Sweden

    Author : Joanna Webb; Lund University.; Lunds universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; apoptosis; binding sites; complement; C4b-binding protein; protein S; Klinisk kemi;

    Abstract : The subject of this thesis is plasma protein C4b-binding protein (C4BP). C4BP is an important regulator of the classical pathway of the complement system, a cascade-like system comprised of over 35 proteins, which partakes in the defence against micro-organisms and is involved of clearance of immune-complexes and apoptotic cells. READ MORE

  5. 5. Protein Interactions Involving the Laminin G-type Domains of Vitamin K-dependent Protein S

    University dissertation from Department of Clinical Chemistry, Lund University

    Author : Petra Evenäs; Lund University.; Lunds universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; tyrosine phosphorylation.; Sky receptor; SHBG-like region; protein S; G domain; Gas6; Activated protein C; C4b-binding protein; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : The studies described in this thesis focus on the involvement of the two laminin G-type domains of vitamin K-dependent protein S in various biological contexts. The G-type domains are located in the C-terminal sex-hormone-binding globulin (SHBG)-like region. READ MORE