Search for dissertations about: "C5a"

Showing result 1 - 5 of 21 swedish dissertations containing the word C5a.

  2. 1. C5a Receptor Expression in Severe Sepsis and Septic Shock

    Author : Mia Furebring; Jan Sjölin; Per Folllin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; C5a receptor; granulocyte; severe sepsis; septic shock; chemotaxis; anti-C5a treatment; ex vivo incubation; C5a; interleukin-8; LPS; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Abstract : In patients with sepsis, the activation of the cascade systems, for example the complement system with the generation of C5a, is followed by a state of immunosuppression with impaired bactericidal capacity caused by suppression of the neutrophil granulocytes. To inhibit the C5a-induced systemic inflammatory and the following anti-inflammatory responses, different anti-C5a strategies have been successful in experimental models of sepsis. READ MORE

  4. 2. The role of the complement system in basal and ischemia-induced neurogenesis

    Author : Yalda Rahpeymai Bogestål; Göteborgs universitet; []
    Keywords : complement; C3a; C5a; adult neurogenesis; neural stem cells; brain ischemia;

    Abstract : .... READ MORE

  5. 3. Molecular analysis of Streptococcus pyogenes and its interactions with the human host

    Author : Andreas Berge; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement activation; fibrinogen; IgG; M protein; C5a peptidase; streptococcal cysteine proteinase; streptokinase; t-PA; Streptococcus pyogenes; plasminogen; C1q; insertional sequence.; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. READ MORE

  6. 4. Regulation of human eosinophil transmigration across lung epithelium

    Author : Lixin Liu; Uppsala universitet; []
    Keywords : Medical sciences; Eosinophils; regulation; migration; epithelial cells; lung; calcium; CD11b CD18; neutrophils; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Abstract : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. READ MORE

  7. 5. Analysis of the molecular interplay between Streptococcus pyogenes and its human host

    Author : Björn Johansson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Biomedicinska vetenskaper allmänt ; Regulation; General biomedical sciences; IdeS; Enzyme; Virulence factors; Virulence; Bacteria; Streptococci; bakteriologi; virologi; mykologi; GAS; Protein; Mikrobiologi;

    Abstract : The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. READ MORE