Search for dissertations about: "C8-oxidation capillary elearophoresis dimethylxanthines high-performance liquidchromatography liver"

Found 1 swedish dissertation containing the words C8-oxidation capillary elearophoresis dimethylxanthines high-performance liquidchromatography liver.

2. 1. Elimination of caffeine metabolites in man

   Author : Nikolaos Rodopoulos; Karolinska Institutet; Karolinska Institutet; []
   Keywords : C8-oxidation capillary elearophoresis dimethylxanthines high-performance liquidchromatography liver cirrhosis N-acetylation N-demethylation monomethylurates monomethylxanthines;

   Abstract : Plasma, saliva and urinary caffeine (CA), paraxanthine (PX), theobromine (TB), theophylline (TP) and their metabolites were, after separation into fractions by reversed-phase high-performance liquid chromatography (HPLC), quantitated by capillary electrophoresis (CE). In healthy adults, 96% of the total amount of excreted compounds derived from CA were dimethylxanthines (DMXs) and metabolites, the remainder 4% being nonmetabolized CA and its non-demethylated urate. READ MORE