Search for dissertations about: "CACNA1D"

Found 2 swedish dissertations containing the word CACNA1D.

  2. 1. Genetic Alterations and Molecular Signatures in Aldosterone Producing Adenomas

    Author : Tobias Åkerström; Peyman Björklund; Tracy Ann Williams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aldosterone; aldosterone producing adenoma; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CTNNB1;

    Abstract : Primary Aldosteronism (PA) is caused by autonomous overproduction of aldosterone. Aldosterone is necessary for fluid and ion homeostasis. Aberrant overproduction leads to hypertension and cardiovascular damage. READ MORE

  4. 2. New aspects of voltage-gated calcium channel regulation in pancreatic beta-cells - Relevance for insulin release and type 2 diabetes

    Author : Thomas Reinbothe; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; voltage-gated calcium channels; L-type; insulin secretion; type 2 diabetes;

    Abstract : Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose lowering hormone insulin. READ MORE