Search for dissertations about: "CAG"

Showing result 6 - 10 of 51 swedish dissertations containing the word CAG.

  2. 6. Strategies for de novo DNA sequencing

    Author : Anna Blomstergren; KTH; []
    Keywords : DNA sequencing; DNA purification; automation; solid-phase; streptavidin; biotin; modular probes; Helicobacter pylori; cag PAI;

    Abstract : The development of improved sequencing technologies hasenabled the field of genomics to evolve. Handling andsequencing of large numbers of samples require an increasedlevel of automation in order to obtain high throughput andconsistent quality. READ MORE

  4. 7. Genetic and Molecular analysis of the Spinocerebellar ataxia type 7 (SCA7) disease gene

    Author : Jenni Jonasson; Monica Holmberg; Christine Van Broeckhoven; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinocerebellar ataxia; human genetics; linkage analysis; anticipation; CAG repeat expansion; founder effect; protein expression; ATXN7; Medical genetics; Medicinsk genetik;

    Abstract : Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disorder affecting the cerebellum, pons and retina. SCA7 patients present with gait ataxia and visual impairment as the main symptoms. READ MORE

  5. 8. Diversity and persistence of Helicobacter pylori

    Author : Annelie Lundin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Helicobacter pylori; genomic diversity; cag pathogenicity island; Nudix hydrolase;

    Abstract : Helicobacter pylori is an exceptionally diverse bacterial species, and every infected individual harbors a unique strain, apart from the strain concordance found in some families. The infection is usually acquired during childhood and once established, persists for life unless treated with antibiotics. READ MORE

  6. 9. Aspects of Helicobacter pylori transmission

    Author : Mårten Kivi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Helicobacter pylori; epidemiology; transmission; family; two-stage; missing data; molecular typing; CagA; cag pathogenicity island; variability; microarray;

    Abstract : The bacterium Helicobacter pylori infects the gastric mucosa of about half of the world's population. The infection causes gastritis and contributes to the development of peptic ulcer disease and gastric cancer. H. READ MORE

  7. 10. Molecular genetic studies on Huntington disease

    Author : Elisabeth Almqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Huntington disease; PCR; predictive testing;

    Abstract : Huntington disease (HD) is an autosomal dominant neurodegenerative disorder associated with an expanded trinucleotide repeat (CAG). Prior to the gene identification in 1993, linkage analysis was used for predictive testing for at-risk individuals. READ MORE