Search for dissertations about: "CAR T cells"
Showing result 11 - 15 of 21 swedish dissertations containing the words CAR T cells.
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11. Improvement of adoptive T-cell therapy for Cancer
Abstract : Cancer immunotherapy has recently made remarkable clinical progress. Adoptive transfer of T-cells engineered with a chimeric antigen receptor (CAR) against CD19 has been successful in treatment of B-cell leukemia. READ MORE
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12. Adenovirus species B: receptors, tropism and hematopoietic cells
Abstract : At present, the human adenoviruses (Ads) comprise 51 members, which have been classified into six species (A to F). In general, adenovirus (Ad) tissue tropism or disease patterns vary according to species, although adenoviruses from different species can sometimes cause the same symptoms. READ MORE
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13. Translational studies of metastatic melanoma in the era of immunotherapy - from humanized mouse models to clinical trials
Abstract : Immunotherapy with PD-1 inhibitors has transformed the treatment of met-astatic cutaneous mela- noma, and can lead to complete and durable responses in a proportion of patients. However, in around half of the patients, the treatment has little or no effect. READ MORE
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14. Glioblastoma multiforme in the microscope: Diagnostic features of importance for prognosis and treatment
Abstract : Glioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. READ MORE
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15. Cellular and personalized therapies in multiple myeloma with special emphasis on retargeted natural killer cells
Abstract : Multiple myeloma (MM) is a clonal plasma cell malignancy accounting for approximately 10% of all hematological cancer cases. Despite considerable advances in MM management, which led to exceptional response and survival rates, patients still experience relapse and cure remains elusive. READ MORE