Search for dissertations about: "CASR"

Showing result 1 - 5 of 7 swedish dissertations containing the word CASR.

2. 1. Growth of parathyroid glands : genetic and functional aspects

   Author : Stiina Välimäki; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Parathyroid; primary hyperparathyroidism; secondary hyperparathyroidism; parathyroid carcinoma; chromosome 1; HDAC1; HRPT2; CASR; CAS; VDR; PTH; loss of heterozygosity; tumor suppressor gene; patch clamp; membrane potential; K channels;

   Abstract : Ca2+ is an essential ion with a variety of important functions in the body and it is crucial that the Ca2+ levels are precisely regulated. One of the hormones regulating these processes is parathyroid hormone (PTH) secreted from the parathyroid glands. READ MORE

4. 2. Sexual Relationships between Athletes and Coaches : Love, Sexual Consent, and Abuse

   Author : Susanne Johansson; Håkan Larsson; Carolina Lundqvist; Kari Fasting; Gymnastik- och idrottshögskolan; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; coach-athlete sexual relationship; sexual harassment and abuse; romantic love; sexual consent; gender and sexuality; power and agency; sport; Samhällsvetenskap Humaniora; Social Sciences Humanities;

   Abstract : Coach-athlete sexual relationships (CASR) and sexual harassment and abuse (SHA) in sport can profoundly impact athletes’ welfare and performance. Yet, it is often ignored due to sensitivity, secrecy, and lack of knowledge. There is no previous research on SHA in sport in Sweden, and legal, consensual, same-sex CASR is under-researched. READ MORE

5. 3. Calcium Homeostasis in Patients with Graves' Disease

   Author : Maria Annerbo; Per Hellman; Peter Stålberg; Peyman Björklund; Filipsson Nyström Helena; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Graves Disease; Calcium homeostasis; Total thyroidectomy; Bone metabolism; Calcium sensing receptor; Surgery; Kirurgi;

   Abstract : Patients with Graves´ Disease (GD) have a higher risk of developing more severe and prolonged hypocalcaemia after total thyroidectomy (TT) than patients who undergo surgery for benign atoxic goitre. Since TT is the most effective treatment for GD, it is crucial to identify mechanisms for postoperative hypocalcaemia. READ MORE

6. 4. New Insights in Genetic and Epigenetic Mechanisms Involved in Parathyroid Tumorigenesis

   Author : Lee Starker; Peyman Björklund; Barbra Miller; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parathyroid; yumorigenesis; mutation; exome sequencing;

   Abstract : Primary hyperparathyroidism (pHPT) is a pathology associated with one or multiple hyperfunctioning parathyroid glands.  The disease prevalence occurs in roughly 1-2% of the population primarily post-menopausal women.  The molecular pathology of the disease is poorly understood. READ MORE

7. 5. Molecular studies of endocrine tumors : Insights from genetics and epigenetics

   Author : Samuel Backman; Per Hellman; Peter Stålberg; Olov Norlén; Robert Bränström; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Carcinoid; Pheochromocytoma; Aldosterone; Cancer; MEN1; Multiple endocrine neoplasia; Medicinsk vetenskap; Medical Science;

   Abstract : Endocrine tumors may be benign or malignant and may occur in any of the hormone producing tissues. They share several biological characteristics, including a low mutation-burden, and may co-occur in several hereditary tumor syndromes. The aim of this thesis was to identify genetic and epigenetic aberrations in endocrine tumors. READ MORE