Search for dissertations about: "CBP"
Showing result 21 - 25 of 31 swedish dissertations containing the word CBP.
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21. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins
Abstract : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. READ MORE
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22. Novel allergen preparations for use in allergen-specific immunotherapy
Abstract : Allergy is a common disease in the industrialized countries, affecting approximately 25% of the population. Therefore, there is a need to find new treatment strategies to improve the quality of life for allergic individuals. Today the only treatment that gives long-lasting reduction of allergic symptoms is allergen-specific immunotherapy (SIT). READ MORE
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23. Molecular mechanisms for lineage-restricted differentiation of adult neural progenitors
Abstract : Aims: In the central nervous system of several species, including humans, neurogenesis per?sists even in the adult life in discrete neurogenic regions of the brain. Adult neural stem cells derived from these neurogenic areas are proliferating cells, which can differentiate to neurons, astrocytes, and oligodendrocytes. READ MORE
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24. Adaptive Microarchitectural Optimizations to Improve Performance and Security of Multi-Core Architectures
Abstract : With the current technological barriers, microarchitectural optimizations are increasingly important to ensure performance scalability of computing systems. The shift to multi-core architectures increases the demands on the memory system, and amplifies the role of microarchitectural optimizations in performance improvement. READ MORE
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25. Pharmacological targeting of mutant p53 family members
Abstract : The tumor suppressor p53 serves as a guardian of the genome and functions mainly as a transcription factor. In response to various stress signals p53 binds to specific DNA sequence motifs and regulates transcription of a large group of target genes involved in cellular processes such as cell cycle arrest, senescence and apoptosis. READ MORE