Search for dissertations about: "CCL11"

Showing result 1 - 5 of 9 swedish dissertations containing the word CCL11.

  2. 1. Novel Insights into Inflammatory Disturbed Bone Remodelling

    Author : Elin Kindstedt; Pernilla Lundberg; Östen Ljunggren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osteoblast; osteoclast; chemokines; CCL11; periodontitis; rheumatoid arthritis; innate lympoid cells; odontologi; Odontology; immunologi; Immunology; biology; biologi; reumatologi; rheumatology;

    Abstract : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. READ MORE

  4. 2. Chemokines and bone : lessons from in vitro and in vivo studies

    Author : Sara Rosendahl; Pernilla Lundberg; Cecilia Koskinen Holm; Elin Kindstedt; Marie Lagerquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Bone homeostasis is maintained by the balanced activity of bone-forming osteoblasts and bone-resorbing osteoclasts. Inflammation in the vicinity of bone disturbs the balanced bone remodeling process, which often results in bone loss. READ MORE

  5. 3. Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology

    Author : Yuri Sheikine; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; coronary artery disease; restenosis; chemokines; eicosanoids;

    Abstract : Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel wall. These processes are mediated, among other substances, by molecules belonging to a large family of chemoattractants. READ MORE

  6. 4. Genetic regulation of neuroinflammation : a translational approach

    Author : Johan Öckinger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), causing demyelination and axonal damage. As other complex diseases with an inflammatory or autoimmune component, MHC is a strong regulator of the disease and acts in concert with multiple nonMHC genes and environmental factors. READ MORE

  7. 5. Inflammation and prostate carcinogenesis : influence of immune characteristics and early-adulthood exposure to inflammatory conditions on prostate cancer risk

    Author : Henrik Ugge; Katja Fall; Sabina Davidsson; Jessica Carlsson; Ove Andrén; Lars Henningsohn; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; inflammation; Cutibacterium acnes; acne; appendicitis; cytokines; circulating; inflammation marker; IL6; CXCL8;

    Abstract : Chronic inflammation has been implicated in the development of several types of cancer, and evidence from observational and animal studies suggests that it may play a role also in prostate carcinogenesis. Recent observations have brought Cutibacterium acnes (C. acnes) forward as a possible causative agent in pro-oncogenic prostatic inflammation. READ MORE