Search for dissertations about: "CCR3"

Showing result 1 - 5 of 15 swedish dissertations containing the word CCR3.

  2. 1. Human eosinophils and their activation by allergens via danger signal receptors

    Author : Elin Redvall; Göteborgs universitet; []
    Keywords : human eosinophils; danger signals; allergen; formyl peptide receptors; CCR3; chemotaxis; degranulation; free oxygen radicals; receptor desensitization;

    Abstract : Human eosinophilic granulocytes are polymorphonuclear cells with a powerful arsenal of cytotoxic substances in their granules, which are mainly found in the gastrointestinal mucosa, and the respiratory and genitourinary tracts. Their physiological role is incompletely understood, although it is likely they protect the mucosal surfaces, perhaps by recognizing danger signals present on microorganisms or released from damaged tissue. READ MORE

  4. 2. Chemokines and bone : lessons from in vitro and in vivo studies

    Author : Sara Rosendahl; Pernilla Lundberg; Cecilia Koskinen Holm; Elin Kindstedt; Marie Lagerquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Bone homeostasis is maintained by the balanced activity of bone-forming osteoblasts and bone-resorbing osteoclasts. Inflammation in the vicinity of bone disturbs the balanced bone remodeling process, which often results in bone loss. READ MORE

  5. 3. Dynamics of HIV coreceptors and their utilization by plasma and cerebrospinal fluid HIV-1 isolates

    Author : Ulf Karlsson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : HIV-1 infection of CD4+ immune cells requires the assistance of cellular coreceptors. The regulation of these receptors is highly dynamic. In addition to the major coreceptors, CCR5 and CXCR4, several alternative coreceptors mediate entry for selected HIV isolates in vitro, although their role in vivo is yet to be established. READ MORE

  6. 4. Novel Insights into Inflammatory Disturbed Bone Remodelling

    Author : Elin Kindstedt; Pernilla Lundberg; Östen Ljunggren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osteoblast; osteoclast; chemokines; CCL11; periodontitis; rheumatoid arthritis; innate lympoid cells; odontologi; Odontology; immunologi; Immunology; biology; biologi; reumatologi; rheumatology;

    Abstract : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. READ MORE

  7. 5. Eosinophils, their progenitors and T helper cells in allergic airway inflammation

    Author : You Lu; Göteborgs universitet; []
    Keywords : eosinophils; eosinophil progenitors; T helper cells; Th2 cells; IL-33; migration; Asthma;

    Abstract : Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and treatment responses in allergic asthma. READ MORE