Search for dissertations about: "CCR5"

Showing result 1 - 5 of 60 swedish dissertations containing the word CCR5.

  1. 1. Recombinant CXCR4/CCR5 hybrid receptors as tools for studies of HIV-1 receptor usage

    University dissertation from Department of Experimental Medical Science, Lund Univeristy

    Author : Liselotte Antonsson; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; evolution; pathogenesis; cerebrospinal fluid; Medicine human and vertebrates ; TAK-779; RANTES; CXCR4; CCR5; coreceptor; GPCR; HIV-1;

    Abstract : Popular Abstract in Swedish Människan är uppbyggd av ett stort antal celler. För att kroppens olika organ ska kunna samverka och för att kroppen ska kunna fungera som en helhet, måste de olika cellerna kommunicera med varandra. Cellernas kommunikationssystem är uppbyggt av mottagare, s.k. READ MORE

  2. 2. Virus tropism and neutralization response in SIV infection

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Anna Laurén; Lunds universitet.; Lund University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Natural science; Medicin människa och djur ; Medicine human and vertebrates ; HIV; SIV; mode of CCR5 use; CD4-independence; macrophage tropism; coreceptor use; neutralization; evolution; pathogenesis;

    Abstract : Popular Abstract in Swedish Sedan 1981, då de första fallen av AIDS beskrevs, har 25 miljoner människor dött på grund av att de har blivit smittade av immunbristviruset HIV . Det finns idag mer än 40 miljoner människor som lever med HIV eller AIDS. READ MORE

  3. 3. HIV-1 patient assessment and treatment -from multitest to co-receptor (CCR5) gene polymorphism -from rgp160 immuniiztion to highly active antiretroviral treatment (HAART)

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Göran Bratt; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : During the last 15 years, understanding of the pathogenesis of HIV- 1 infectionand AIDS has developed rapidly. From a mysterious plague-like untreatable diseasewith unknown cause and transmission route to a well characterized, chronic, manageable,if yet not curable, retroviral infection. READ MORE

  4. 4. Targeting HIV-1 entry and reverse transcription by vaccination

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Bartek Zuber; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; DNA vaccination; coreceptor; CCR5; RT; drug resistance; CpG; pseudovirus;

    Abstract : Human immunodeficiency virus type I (HIV-1) is a complex retrovirus, which uses the CD4 receptor and chemokine receptors to infect its target cells. The chemokine receptor CCR5 is essential for primary HIV-1 infection. The hallmark of retroviruses is the enzyme reverse transcriptase (RT), which transcribes the virus genome from RNA to DNA. READ MORE

  5. 5. Viral parameters influencing clinical long-term non progression in HIV-1 infected subjects

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Ubaldo Visco Comandini; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTNP; HIV-1 DNA; HIV-1 RNA; quantification; spontaneous decrease; genetic heterogeneity; nef; LTR; CCR5 deletion;

    Abstract : A very small portion of the HIV-1 infected population is constituted by individuals, called long- term non progressors (LTNP), in whom after even a decade or more, no visible deterioration of the immune system is recognized and the infection remains therefore asymptomatic. The reasons for such "natural" prolonged well-being can be attributed to both the virus and the infected host and their understanding is likely to give important information for the development of an effective HIV- vaccine and for immune reconstitution therapy. READ MORE