Search for dissertations about: "CD11c"
Showing result 1 - 5 of 27 swedish dissertations containing the word CD11c.
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1. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation
Abstract : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. READ MORE
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2. Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies
Abstract : Antibodies can enhance or suppress the immune responses against their specific antigens. This phenomenon is known as antibody-mediated feedback regulation. We have studied the mechanisms underlying IgE-, IgM-, and IgG3-mediated enhancement of immune responses in mouse models using intravenous immunization. READ MORE
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3. Sarcoma ecosystems : spatial characterization and prognostic significance
Abstract : Sarcoma is a highly heterogeneous disease with complex biological activities and unique tumor microenvironments (TME) in distinct subtypes. The limited treatment options and inadequate responses to current therapies necessitate a deeper understanding of sarcoma biology and personalized treatment strategies. READ MORE
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4. Yersinia-phagocyte interactions during early infection
Abstract : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. READ MORE
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5. Beyond Th1 and Treg : intestinal T helper cells in disease and tolerance
Abstract : The human intestinal tract is not only one of the largest organs by surface area in our bodies but also harbors the greatest number of immune cells. These cells are crucial for maintaining tolerance towards the various food and microbial antigens and mounting protective inflammatory responses towards invading pathogens. READ MORE