Search for dissertations about: "CD34 enrichment"

Found 3 swedish dissertations containing the words CD34 enrichment.

2. 1. Fetal hematopoietic cells in early gestation : aspects in view of fetal transplantation

   Author : Sverker Ek; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Fetal stem cells; fetal liver; fetal hematopoiesis; immunological ontogeny; fetal transplantation; cytokines; CD34 enrichment;

   Abstract : The fetus as a patient is a challenge. There are opportunities for early, sometimes life-saving procedures or there may be advantages in prenatal rather than postnatal intervention. This is the case in fetal hematopoietic cell (FHC) transplantation where conditions caused by a defect in blood cell formation may be life-threatening to the fetus. READ MORE

4. 2. Individualized leukapheresis of hematopoietic cells for cellular therapies

   Author : Anna Mårtensson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Leukapheresis; hematopoietic stem cell; CD34; monocyte; on-line sample; prediction;

   Abstract : Hematopoietic stem and progenitor cells from blood (HSC) are collected by leukapheresis from patients after mobilization with G-CSF +/- chemotherapy to be used in autologous transplantation. The established method to measure the content of HSC in peripheral blood and HSC collections is by their expression of the CD34-antigen. READ MORE

5. 3. Clinical and molecular effects of azacitidine in the myelodysplastic syndromes

   Author : Magnus Tobiasson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The myelodysplastic syndromes (MDS) constitute a heterogeneous group of malignant bone marrow disorders characterized by peripheral cytopenia and increased risk of leukemic progression. In higher-risk MDS, Azacitidine has been shown to prolong survival and modulate the epigenome, although the precise mechanisms by which the drug exerts its effect are unknown. READ MORE