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Showing result 1 - 5 of 30 swedish dissertations matching the above criteria.

  1. 1. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?

    Author : Linda Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; diabetes CD14; CD36; CD64; fatty acid; flow cytometry; macrophage; monocyte; scavenger receptor;

    Abstract : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. READ MORE

  2. 2. Computational and experimental approaches to regulatory genetic variation

    Author : Malin Andersen; Jacob Odeberg; John Peden; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Molecular biology; Genetics; single nucleotide polymprhism SNP ; regulatory SNP; transcription factor binding site; phylogenetic footprinting; allelic imbalance; EMSA; CD36; cardiovascular disease.; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Genetic variation is a strong risk factor for many human diseases, including diabetes, cancer, cardiovascular disease, depression, autoimmunity and asthma. Most of the disease genes identified so far alter the amino acid sequences of encoded proteins. READ MORE

  3. 3. Regulation of epithelial morphogenesis in Drosophila by the Emp scavenger receptor

    Author : Ana Sofia Pinheiro; Christos Samakovlis; Sofia Araújo; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Emp; scavenger receptor; CD36; cytoskeleton; Src kinase; Diap; DrICE; Hipo Yki; endocytosis; Drosophila; airways; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The respiratory system of Drosophila melanogaster, the trachea, is widely used as a model system to study the development of branched tubular organs. Airway maturation in Drosophila entails a series of sequential events: first, a massive apical secretion of luminal proteins initiates diametric tube expansion, second an endocytic wave removes luminal proteins and finally liquid clearance and gas filling converts the nascent epithelial tubes to a functional respiratory organ. READ MORE

  4. 4. Receptors and Regulators of Myeloid Leukemia

    Author : Sofia von Palffy; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CML; AML; cell surface receptors; leukemic stem cells; IL1RAP; CD36; C3AR;

    Abstract : .... READ MORE

  5. 5. Targeting Nutrient Transporters in Acute Myeloid Leukemia

    Author : Hannah Åbacka; Medicinsk strukturbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Akut myeloisk leukemi; Metabolism; Transportörer; GLUT1; GLUT4; CD36; AQP7; ASPL; Inhibitor; Glukos; Fettsyra; Glycerol; Acute myeloid leukemia; Metabolism; Transporter; GLUT1; GLUT4; CD36; AQP7; ASPL; Small-molecule inhibitor; Glucose; Fatty acid; Glycerol;

    Abstract : .... READ MORE