Search for dissertations about: "CD36"

Showing result 21 - 25 of 30 swedish dissertations containing the word CD36.

  2. 21. Central adipocyte functions in specialized caveolae

    Author : Unn Örtegren Kugelberg; Eva Degerman; Linköpings universitet; []
    Keywords : Obesity; Overweight; Diabetes; Stroke; Cholesterol metabolism; Fatty acids; MEDICINE; MEDICIN;

    Abstract : Obesity and overweight is an increasing health problem in the world. Besides reducing quality of life obesity is a great risk factor for development of diseases such as type 2 diabetes, cardiovascular disease, and stroke. The adipose tissue is a flexible organ that grows in size if the body is provided with excess energy. READ MORE

  4. 22. Role of cholesterol metabolism in hepatic steatosis and glucose tolerance

    Author : Osman Salih Osman Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The liver is the central organ for lipid, lipoprotein and glucose homeostasis, thus hepatic metabolic disturbances can predispose individuals to develop cardiometabolic disorders (CMD) such as atherosclerotic cardiovascular diseases (ASCVD), type 2 diabetes mellitus (T2DM), and nonalcoholic fatty liver disease (NAFLD).The overall aim of this thesis was to expand the knowledge on how genetic and pharmacological interventions on hepatic and intestinal cholesterol metabolism could affect the pathophysiology of CMD. READ MORE

  5. 23. Gene expression profiling in molecular studies of hormone actions

    Author : Nina Ståhlberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Although the link between hormones and their physiological effects have been known for a long time, large pieces are still missing in our understanding of how these extracellular signals induce their effects at the cellular level. Signal transduction studies have gathered plenty of information about hormone signaling, but the complex network of interactions between different hormones, signaling pathways and cell types is still not completely understood. READ MORE

  6. 24. Exosomes from lung and breast milk : regulators of immune responses

    Author : Patricia Torregrosa Paredes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Exosomes are key mediators of intercellular communication with the capacity to regulate immune responses, locally and distally. Most knowledge on exosomal function has been gained from exosomes generated from in vitro cell cultures, which has helped define the role of exosomes from specific cell types. READ MORE

  7. 25. Cellular immunity and inflammation in atherosclerosis

    Author : Dirk Marcus Wuttge; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; T cell; oxLDL; malondialdehyde; hapten; posttranslational; interleukin-] 5; retinoic acid receptor; inflammation;

    Abstract : Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the subendothelial space, where compounds inside of LDL are chemically modified through lipid peroxidation. READ MORE