Search for dissertations about: "CD4 T cells"

Showing result 21 - 25 of 496 swedish dissertations containing the words CD4 T cells.

  1. 21. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Author : Carina Lundqvist; Marie-Louise Hammarström; Sten Hammarström; Per Brandtzaeg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Abstract : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. READ MORE

  2. 22. Binding Kinetics of Proteins at Immune-Cell Contacts

    Author : Manto Chouliara; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; T cells; Binding Kinetics; Affinity; Lifetime; CD4; CD2; TIRF Microscopy; SLBs;

    Abstract : Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. READ MORE

  3. 23. T cells in chronic obstructive pulmonary disease

    Author : Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Abstract : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. READ MORE

  4. 24. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Author : Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Abstract : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. READ MORE

  5. 25. CD4+CD25+ T regulatory cells in multiple sclerosis

    Author : Prabhakar Putheti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). READ MORE