Search for dissertations about: "CD4 cell decline"

Showing result 1 - 5 of 28 swedish dissertations containing the words CD4 cell decline.

  2. 1. Immunomodulatory Effects of Human ImmunodeficiencyVirus (HIV-1) on Dendritic Cell and T cell Responses : Studies of HIV-1 effects on Dendritic cell functionality reflected in primed T cells

    Author : Karlhans Fru Che; Marie Larsson; Jorma Hinkula; Karl-Eric Magnusson; Douglas Nixon; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The human immunodeficiency virus (HIV)-1 is the causative agent of acquired immune deficiency syndrome (AIDS) worldwide. Till date there are no vaccines or cure for this infection as the virus has adapted myriad ways to remain persistent in the host where it causes severe damage to the immune system. READ MORE

  4. 2. Anti-citrulline immunity in rheumatoid arthritis : characterization of peptide-HLA interactions and CD4+ T cell responses

    Author : Christina Gerstner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid Arthritis (RA) is a complex, systemic autoimmune disorder characterized by chronic inflammation in small joints in hands and feet. It is a common disease that if untreated leads to joint destruction, disability, comorbidities and a reduced lifespan. READ MORE

  5. 3. The central role of the CD4 T-helper cell in HIV infection : analysis of cell mediated responses and CCR-5 genotypes in HIV-1 infected individuals

    Author : Ann-Charlotte Leandersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human immunodeficiency virus (HIV) infection is characterized by progressive immunologic dysregulation. The main target of HIV is the CD4 cell resulting in malfunction of the immune system, with a decline in CD4 cells and subsequent development of the acquired immunodeficiency syndrome (AIDS). READ MORE

  6. 4. Living and Dying with Primary Sjögren's Syndrome Studies on Aetiology, Treatment, Lymphoma, Survival and Predictors

    Author : Elke Theander; Internmedicin - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; transplantation; muskelsystem; Skelett; rheumatology locomotion; long-term outcome; Sjögren s Syndrome; Helicobacter pylori infection; prospective cohort studies; SMR; SIR for lymphoproliferative disease; fatigue; health-related quality of life; complement function; oncology; Cytologi; Immunology; cancer; serologi; Immunologi; serology; cancerology; onkologi; reumatologi; muscle system; CD4 T-lymphocytopenia; Cytology;

    Abstract : This work was aimed at improving our understanding of the course of primary Sjögren's syndrome (SS). The Malmö SS patient register and the 2002 American-European Consensus Criteria formed the basis of all studies. Helicobacter pylori (H. READ MORE

  7. 5. Exploring the complexity of functional hiv-1 specific t-cell responses and global virus-host genetic variability

    Author : Carina Pérez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : HIV has become one of the biggest health problems up to date. After 30 years of tremendous effort, the development of an HIV vaccine is still far from achieved. One of the main issues is the high mutation rate of the virus which results in the selection of mutated variants. READ MORE