Search for dissertations about: "CD44"

Showing result 1 - 5 of 58 swedish dissertations containing the word CD44.

  1. 1. A role of CD44 in atherosclerosis? Studies in mice and humans

    Author : Sara Sjöberg; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD44; atherosclerosis; interleukin-6; T cell; mast cell;

    Abstract : Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the cell surface, and soluble CD44 can be detected in blood. READ MORE

  2. 2. Regulation of Hyaluronan Synthesis and Signaling via CD44 in Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Merima Mehić; Paraskevi Heldin; Carl-Henrik Heldin; Liliana Schaefer; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyaluronan; CD44; TGFβ; PDGF-BB; cancer; signaling; hyaluronan synthase; epithelial-mesenchymal transition; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Medical Science; Medicinsk vetenskap;

    Abstract : Hyaluronan is a ubiquitous glycosaminoglycan which is an important constituent of the extracellular matrix (ECM). In addition to organizing the extracellular matrix and regulating tissue homeostasis, hyaluronan, by binding to its main cell surface receptor CD44, is involved in intracellular signaling pathways regulating major cellular processes during development, wound healing, inflammation and cancer. READ MORE

  3. 3. Effect of Hyaluronan-activation of CD44 on Cell Signaling and Tumorigenesis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lingli Li; Paraskevi Heldin; Raija H. Tammi; [2006]
    Keywords : Biomedicine; Hyaluronan; CD44; growth factors; chemokines; tumorigenesis; wound healing; cell signaling; Biomedicin;

    Abstract : Hyaluronan (HA), a structural component in the extracellular matrix (ECM), has been recognized as a signaling molecule. It is important during various biological activities such as embryogenesis, angiogenesis, wound healing and tumor progression. READ MORE

  4. 4. Hyaluronan and the receptor CD 44 in the heart and vessels a study in normal and pathological conditions

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Martin Hellström; Anna Engström-Laurent; Bengt Johansson; Lena Jonasson; [2007]
    Keywords : hyaluronan; CD44; heart; Rat; cardiac hypertrophy; artery; vein; human; Medicine; medicin;

    Abstract : Tissues are not solely composed of cells. The extracellular matrix is important for the cell well-being and cell-cell communication. The glycosaminoglycan hyaluronan (HYA) is a widely distributed extracellular matrix (ECM) component. READ MORE


    University dissertation from Surgery Research Unit

    Author : Zirak Hasan; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil; lung; chemokines; infection; T-cells; CD44; Rho-kinase; isoprenylation;

    Abstract : Sepsis and subsequent organ failure remain the major cause of mortality in intensive care units in spite of significant research efforts. The lung is the most vulnerable organ affected by early hyper-inflammatory immune response in septic patients. READ MORE