Search for dissertations about: "CD44"

Showing result 11 - 15 of 66 swedish dissertations containing the word CD44.

  2. 11. Stem and progenitor cells in brain ad breast malignancies

    Author : Gabriella Honeth; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural progenitor cells; glioma; migration; chemokines; cancer stem cells; breast cancer; CD44; CD24;

    Abstract : Stem cells have qualities that clearly distinguish them from all other cells. Capabilities like self-renewal, differentiation and migration make them truly powerful. This thesis deals with different aspects of stem/progenitor cells in relation to cancer. READ MORE

  4. 12. Colorectal cancer and radiation response : The role of EGFR, AKT and cancer stem cell markers

    Author : Sara Häggblad Sahlberg; Bo Stenerlöw; Bengt Glimelius; Marika Nestor; Torgny Stigbrand; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; colorectal cancer; radiation; AKT; EGFR; cancer stem cells; CD133; CD44; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Abstract : The primary treatment for colorectal cancer is surgery. Radiotherapy and chemotherapy, sometimes combined, are also frequently used to diminish recurrence risk. In response to radiation exposure, several cellular signaling cascades are activated to repair DNA breaks, prevent apoptosis and to keep the cells proliferating. READ MORE

  5. 13. Mechanisms of neutrophil recruitment in septic lung injury

    Author : Karzan Palani; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; infection; neutrophil; lung; chemokines; apoptosis; CD44; F-actin; peptides;

    Abstract : Sepsis is one of leading cause of death despite aggressive surgical intervention and antibiotic therapies. Excessive neutrophil recruitment is a major feature in early phase with immune system dysfunction at later phase. Lung is the most vulnerable, critical and sensitive organ during sepsis process. READ MORE

  6. 14. Importance of Hyaluronan Metabolism and Signalling in Tumour Progression

    Author : Berit Bernert; Paraskevi Heldin; Peter Prehm; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyaluronan; CD44; cancer; growth factors;

    Abstract : Hyaluronan, an unbranched glycosaminoglycan of the extracellular matrix, has an amazingly simple structure. Initially thought to fulfil only hydrating and space-filling functions in tissues, evidence generated during the past decades shows that hyaluronan is involved in intriguingly complex signalling events in health and disease. READ MORE

  7. 15. Stromal and tumor cell responses to hypoxia and treatment within the glioma microenvironment

    Author : Vasiliki Pantazopoulou; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; glioblastoma; tumor microenvironment; reactive astrocytes; hypoxia; CD44; p75NTR;

    Abstract : Glioblastoma is the most aggressive primary brain tumor in adults. Despite treatment, tumors invariably recur, and the recurring tumor is resistant to therapies. New approaches are needed for the successful treatment of glioblastoma patients.Tumors are not simply a compilation of molecularly and phenotypically identical neoplastic cells. READ MORE