Search for dissertations about: "CD57 analysis"

Found 5 swedish dissertations containing the words CD57 analysis.

  2. 1. Human natural killer cell activation and differentiation in health and viral infection

    Author : Niklas Björkström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Natural killer (NK) cells are lymphocytes that belong to the innate immune system. They are important for the early defense against viral infections and provide tumor Immune surveillance against both solid tumors and leukemias as well as in settings of hematopoietic stem cell transplantation. READ MORE

  4. 2. T cell antigen receptor usage, phenotype and cytokine production in human diseases

    Author : Jan Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : T cell; T cell receptor; T cell expansion; phenotype; cytokine; extrinsic allergic alveolitis; allergic asthma; multiple myeloma; Wegener s granulomatosis; sarcoidosis;

    Abstract : T lymphocytes are of critical importance for initiating and controlling immune responses, as the T cell receptor (TCR) for antigen allows a highly specific antigen recognition. Determination of TCR usage and characterization of T cell subsets in different diseases helps us understand the underlying immunopathogenic mechanisms, and may also lead to the development of new therapeutic approaches. READ MORE

  5. 3. The ontogeny and regulation of human natural killer cells

    Author : Martin A Ivarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Natural Killer (NK) cells are members of the innate lymphoid cell (ILC) family and take part in the detection and eradication of virus-infected and transformed cells. In this thesis, together with my colleagues I have investigated how NK cells and other ILCs develop and function during human fetal development, how NK cells are functionally regulated (educated) via the activating receptor KIR2DS1, and how NK cells in our body are affected during the early phase of an acute viral infection. READ MORE

  6. 4. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

    Author : Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. READ MORE

  7. 5. Humanized mice as a model to study human immunity

    Author : Frank Heuts; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mice with human immune systems have evolved over the last three decades. Over the years, these humanized mouse models have provided us with valuable information on human immunity. Recent developments in recipient mouse strains and engraftment protocols have resulted in models with high level of de novo formation of human immune cells. READ MORE