Search for dissertations about: "CD62L"

Showing result 1 - 5 of 10 swedish dissertations containing the word CD62L.

  1. 1. The role of granulocyte antibodies in monocyte and granulocyte activation

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Agneta Wikman; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ANCA; adhesion molecules; CD11b; CD62L; granulocyte antibodies; granulocytes; monocytes; systemic vasculitis;

    Abstract : Granulocytes and monocytes are important cells during the first phase of inflammation. They are activated and recruited from the blood vessels to inflammatory sites via the regulation of receptors involved in adhesion to endothelium. READ MORE

  2. 2. Genetic and immunological studies of DCIR in inflammatory arthritis

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Carina Eklöw; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Rheumatoid arthritis (RA) is a clinically heterogeneous condition with a wide spectrum of clinical manifestations, great variability in severity and disease progression rate. Thus, it is important to define new genetic and immunological markers, which could be useful for sub-grouping of RA, and for new targeted therapies. READ MORE

  3. 3. Modulation of adhesion molecules on leukocytes during clinical and experimental hemodialysis : endothelial cell interacions

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Pia Thylén; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion; adhesion molecules; complement; endothelial cells; hemodialysis; integrins; interleukin; leukocytes; selectins.;

    Abstract : Modulation of adhesion molecules on leukocytes during clinical and experimental hemodialysis - endothelial cell interactions Pia ThylenIn patients on hemodialysis the sequential steps required for adhesion molecule mediated ad-herence of leukocytes to endothelial cells are unphysiologically disrupted since cell activationwith subsequent alterations in adhesion molecule phenotypes takes place in the extracorporealcircuit far away from the respective endothelial cell ligand.The aims of the present investigations were to study the changes in adhesion molecule phenotypeson inflammatory cells induced by clinical and experimental hemodialysis and the consequenceswith regard to the capacity of the cells to adhere to endothelial cells. READ MORE

  4. 4. Innovative approaches to study basophil function in inflammation

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Zenib Aljadi; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Basophils are circulating granulocytes. They are very rare and represent less than 1% of peripheral blood leukocytes. Basophils connect the innate and adaptive immune responses by the secretion of a variety of immune-mediators involved in the pathogenesis of many inflammatory diseases mainly allergic reactions and autoimmune diseases. READ MORE

  5. 5. Innate mechanisms in upper airway inflammation with focus on epithelium and neutrophils

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Author : Julia Arebro; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Mucosal inflammation is a key feature in allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP). The traditional idea of the epithelium as a simple barrier and neutrophils as a homogenous cell population, already terminally differentiated, has lately been reconsidered. READ MORE