Search for dissertations about: "CD68"

Showing result 6 - 10 of 42 swedish dissertations containing the word CD68.

  1. 6. HIV target cells and innate immune factors in the human female genital tract

    Author : Tove Kaldensjö; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : World-wide, human immunodeficiency virus (HIV) transmission most often takes place in the genital tract during heterosexual intercourse, but the site where HIV most commonly establishes primary infection in the female genital tract remains unknown. Several factors including viral load in the HIV-infected individual, presence of genital infections, genotype and possibly sex hormone levels influence the risk of HIV acquisition. READ MORE

  2. 7. Glioblastoma multiforme in the microscope: Diagnostic features of importance for prognosis and treatment

    Author : Annette Persson; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; cytogenetik; Genetik; Genetics; cytogenetics; Medicin människa och djur ; macrophages; adenoviral based gene-therapy proliferation activity; telomerase activity; immunohistochemistry; Medicine human and vertebrates ; cytotoxic T-lymphocytes; diagnostic features; prognosis; immuno-therapy; Glioblastoma multiforme; neuropathology; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Abstract : Glioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. READ MORE

  3. 8. Peri-implantitis and periodontitis. Experimental and clinical studies

    Author : Olivier Carcuac; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dental implant; animal experiment; biopsy; radiology; histology; immunohistochemistry; inflammation; peri-implant disease; periodontal disease; treatment; systemic antibiotics; antiseptics;

    Abstract : Peri-implantitis is an increasing problem in implant dentistry. The current series of studies employed a translational approach with the aim to compare peri-implantitis and periodontitis lesions and evaluate the influence of implant surface characteristics and the adjunctive use of systemic antibiotics/local antiseptics on healing following surgical treatment of peri-implantitis. READ MORE

  4. 9. Mutation and immune profiling of non-small cell lung cancer

    Author : Linnéa La Fleur; Johan Botling; Fernando López-Ríos; Uppsala universitet; []
    Keywords : Non-small cell lung cancer; Tumor microenvironment; Tumor-associated macrophages; Immune infiltrates; PD-L1; Mutation patterns; Immune therapy; MARCO; TP53; STK11; KRAS;

    Abstract : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. READ MORE

  5. 10. Acute pancreatitis, from local defense to remote organ injury

    Author : Hamid Akbarshahi; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; heparan sulfate; damage associated molecular patterns; toll-like receptor4; MyD88; IRF-3; acute lung injury; macrophages; transforming growth factor-beta; Smad;

    Abstract : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). READ MORE