Search for dissertations about: "CD8 γδ T cells"

Showing result 1 - 5 of 10 swedish dissertations containing the words CD8 γδ T cells.

  2. 1. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Author : Carina Lundqvist; Marie-Louise Hammarström; Sten Hammarström; Per Brandtzaeg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Abstract : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. READ MORE

  4. 2. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Author : Silvia Melgar; Nadine Cerf-Bensussan; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Abstract : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. READ MORE

  5. 3. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

  6. 4. Immune maturation and lymphocyte characteristics in relation to early gut bacteria exposure

    Author : Sophia Björkander; Eva Sverremark Ekström; Hanne Frøkiær; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Allergy; cell-free supernatant; chemokines; colonization; cytokines; FOXP3; immune-maturation; lactobacilli; lymphocytes; NK-cells; Staphylococcus aureus; unconventional T-cells; molekylär biovetenskap; Molecular Bioscience;

    Abstract : At birth, the immune system is immature and the gut microbiota influences immune maturation. Staphylococcus aureus (S. aureus) and lactobacilli are part of the neonatal gut microbiota and have seemingly opposite effects on the immune system. S. READ MORE

  7. 5. Characterization of human gamma delta T cells in allogeneic hematopoietic stem cell transplantation

    Author : Ahmed Gaballa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Over the last five decades, allogeneic hematopoietic stem cell transplantation (HSCT) has evolved rapidly, continuing to offer a cure for several hematological diseases. Nevertheless, associated life-threatening complications remain an obstacle against exploiting its full therapeutic benefit. READ MORE