Search for dissertations about: "CDK"

Showing result 11 - 15 of 43 swedish dissertations containing the word CDK.

  2. 11. Cell Cycle Regulation in Human Renal Cell Carcinoma

    Author : Ylva Hedberg; Göran Landberg; Börje Ljungberg; Göran Roos; Ulf Bergerheim; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human Renal Cell Carcinoma; Cell Cycle; G1 S; Protein; Cyclin; p27; pRb; Phosphorylation; Tissue Microarray; Clinical Behaviour; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : ABSTRACTCell cycle regulation in human renal cell carcinomaYlva Hedberg, Departments of Medical Biosciences, Pathology, and Surgical andPerioperative Sciences, Urology Andrology, Umeå University, SwedenDeregulated growth control is a hallmark of neoplasia potentially caused by aberrant expression of cell cycle regulatory proteins. The importance of such aberrations in human renal cell carcinoma (RCC) has not been fully clarified. READ MORE

  4. 12. Regulation of normal and cancer cells as a base for cell cycle-targeted therapy

    Author : Regina Miftakhova; Malmö Experimentell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell cycle regulation; cyclin A1; stem cells; stem cell niche; epigenetics; cancer;

    Abstract : The majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. READ MORE

  5. 13. In vivo studies of cell cycle regulating proteins in rats during liver regeneration and during promotion of liver carcinogenesis

    Author : Lena Ohlson; Inger Porsvh Hällström; Galina Selivanova; Bertha A. Brodin; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell cycle; cancer; HCC; p53; Rb; p107; G1-progression; G1 S transition;

    Abstract : There are more than one hundred different types of cancer in humans. However, the major platform for all types of cancer is automous and uncontrolled cell division and though most types of cancer are possible to treat and cure by surgery, chemical therapy or irradiation, more efficient and less toxic therapies are urgently needed. READ MORE

  6. 14. Immunofluorescence studies on the cell cycle expression of cyclin A and cyclin E

    Author : Fredrik Erlandsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cell cycle regulation; cyclin A; cyclin E; immunofluorescence staining;

    Abstract : Cell cycle progression is tightly regulated in normal eucaryotic cells. Cancer is caused by the transformation of cells, and is always associated with defects in the cell cycle regulatory machinery. READ MORE

  7. 15. Effects of Hemoglobin Normalization with Epoetin in Chronic Kidney Disease

    Author : Hans Furuland; Björn Wikström; Torbjörn Linde; Peter Barany; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; Anemia; blood viscosity; cardiac output; chronic kidney disease; renal dialysis; dialysis adequacy; erythopoietin; heart rate variability; hemoglobin; hemorheology; hypertension; kidney transplantation; Kt V; left ventricular hypertrophy; Quality of Life; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Abstract : Anemia is common in patients with chronic kidney disease (CDK), contributes to reduced Quality of Life (QoL) and is associated with cardiovascular disease, morbidity and mortality. Epoetin raises hemoglobin (Hb) and increases QoL and physical exercise capacity. READ MORE