Search for dissertations about: "CGD"

Showing result 1 - 5 of 9 swedish dissertations containing the word CGD.

  2. 1. Mechanisms and treatment options of chronic graft dysfunction : Experimental and clinical studies

    Author : Lilija Zezina; Uppsala universitet; []
    Keywords : Medical sciences; chronic graft dysfunction; kidney transplantation; aorta transplantation; lipid oxidation; LDL; TGF-beta; Smad2; angiotensin II receptor; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Chronic graft dysfunction (CGD) is an important post-transplant complication. CGD can be considered as an impaired repair process, which ultimately leads to the loss of graft function.To study non-immunological factors contributing to the development of CGD in kidney grafts we used in vitro and in vivo models, and clinical studies. READ MORE

  4. 2. Symbiotic and pathogenic factors in plant-microbe interaction: Structural basis of C-glycoside metabolism and lipoprotein transport in bacteria

    Author : Valentina Furlanetto; Christina Divne; Mats Sandgren; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Plant-Bacteria Interaction; Symbiotic Communication; C-Glycosylated Compounds; Enzymatic Deglycosylation; Pathogenic Interactions; Lipoprotein Localization; Lol System; Biotechnology; Bioteknologi;

    Abstract : The communication between plants and bacteria involves a complex chemical signaling network that mediates responses to various biotic and abiotic stresses, as well as establishing symbiotic relationships between different organisms.The first part of the thesis focuses on a mechanism for symbiotic communication between plants and bacteria and more specifically on how C-glycosylated aromatic polyketide compounds produced by plants can be used as a mechanism for plants to communicate with beneficial bacteria. READ MORE

  5. 3. Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation

    Author : Martina Sundqvist; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neutrophils; reactive oxygen species; galectin-3; PFAPA;

    Abstract : The focus for this PhD project has been to investigate neutrophil functions in different (inflammatory) settings with specific focus on phagocyte-derived intracellular reactive oxygen species (ROS) as well as neutrophil interaction with the inflammatory mediator galectin-3. Neutrophils, the most abundant leukocyte in human blood, have traditionally been viewed upon mainly as professional phagocytes, being able to degrade invading microbes, and thus essential in the defence against infection. READ MORE

  6. 4. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide

    Author : Gerd Lärfars; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Polymorphonuclear granulocytes; inflammation; nitric oxide; leukotrienes; tumor necrois factor; rheumatoid arthritis; interferon-gamma; chronic granulomatous disease;

    Abstract : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. READ MORE

  7. 5. The role of macrophages in regulating inflammation by oxidative burst

    Author : Angela Pizzolla; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The production of reactive oxygen species (ROS) through a process called oxidative burst is an essential defence mechanism against pathogens. In phagocytes, such as neutrophils and macrophages, the NADPH oxidase 2 (NOX2) complex is the main source of ROS. READ MORE