Search for dissertations about: "CGRP"

Showing result 16 - 20 of 81 swedish dissertations containing the word CGRP.

  2. 16. Sensory neuropeptides and nitric oxide in nasal vascular regulation

    Author : Johan Rinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory nerves; neuropeptides; nasal mucosa; nitric oxide; vascular regulation; acoustic rhinometry; NK1-receptors; CGRP-receptors; vanilloid receptors; capsaicin; lactic acid; exercise; a-adrenoceptor agonists; pig; human.;

    Abstract : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. READ MORE

  4. 17. Immunocytochemical studies of cutaneous nerves in human normal and prurigo nodularis skin

    Author : Yong Liang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Axon; CGRP; ECP; EDN EPX; eosinophil; histamine; HLA-DR; immunoelectron microscopy; Langerhans cell; mast cell; NSE; nerve fiber; p75 NGFr; PGP 9.5; prurigo nodularis; S-100; Schwann cell;

    Abstract : Cutaneous nerves may regulate the immune system and be involved in inflammatory events of the skin. Prurigo nodularis is a skin disease which histologically reveals a massive neural hyperplasia and a local inflammation in the lesional skin. READ MORE

  5. 18. Contributions of calcitonin gene-related peptide in ischemia, inflammation and nociception

    Author : Gunilla Brodda Jansen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 5-hydroxytryptamine; acupuncture; blood flow; calcitonin gene-related pep- tide; edema formation; histamine; inflammation; ischemia; mast cells; neuropeptides; neutrophils; nociception; sensory stimulation; substance P; surgical flaps; withdrawal res;

    Abstract : The sensory neuropeptide Calcitonin gene-related peptide (CGRP) is a very potent vasodilator with a wide distribution in peripheral sensory nerves, often co-stored with substance P. In the present study, the effects of CGRP in different models of ischemia, inflammation and nociception were examined. READ MORE

  6. 19. Vasomotor symptoms in postmenopausal women : the role of acupuncture and calcitonin gene-related peptide

    Author : Yvonne Wyon; Britt-Marie Landgren; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : A majority of postmenopausal women experience vasomotor symptoms, which have a significant impact on the women's quality of life. Estrogens are the treatment of choice but can for different reasons not be used by all women. There is therefore a great need for viable alternative treatments. READ MORE

  7. 20. Pathophysiological mechanisms involved in flap ischemia and its treatment : an experimental study with emphasis on the effects of calcitonin gene-related peptide and spinal cord stimulation on ischemia and manipulation of microcirculation in flaps

    Author : Giulio Gherardini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ischemia; microcirculation; Calcitonin gene-related peptide; spinal cord stimulation;

    Abstract : Flap surgery and microsurgery have expanded the therapeutic options of reconstructive surgery. Partial or total flap necrosis, due to circulatory and metabolic events, is, however, still a significant problem for the plastic surgeon. READ MORE