Search for dissertations about: "CHD"

Showing result 11 - 15 of 127 swedish dissertations containing the word CHD.

  2. 11. Molecular regulation of microsomal triglyceride transfer protein gene, MTP : functional genetic studies in relation to cardiovascular disease

    Author : Helena Ledmyr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Microsomal triglyceride transfer protein; polymorphism coronary heart disease; CHD; cardiac lipid metabolism; protein function; functional promoter studies;

    Abstract : The microsomal triglyceride transfer protein, MTP, is expressed mainly in the liver, intestine and in the heart. It is crucial for the assembly and secretion of apob-containing lipoproteins, chylomicrons in the intestine and very-low density lipoproteins (VLDL) in the liver. READ MORE

  4. 12. Effects of triglycerides on the endothelium

    Author : Pia Lundman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; coronary heart disease CHD ; endothelial function; vasodilation; nitric oxide NO ; hypertriglyceridaemia; triglycerides; free fatty acids; ADMA; cellular adhesion molecules; von Willebrand factor.;

    Abstract : Hypertriglyceridaemia (HTG) is a risk factor for coronary heart disease (CHD), although the mechanisms behind the increased risk remain to be defined. It is unclear whether atherogenic or thrombogenic factors are involved, or a combination thereof the endothelium is important in maintaining normal vascular function and has a key role in atherogenesis. READ MORE

  5. 13. Congenital Heart Disease, Type 1 and Type 2 Diabetes Mellitus

    Author : Anna Björk; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Congenital Heart Disease; Diabetes Mellitus; Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus; Mortality; Morbidity;

    Abstract : Worldwide, 1% of all live born children are born with a congenital heart disease (CHD) and currently >95% reach adulthood due to better diagnostics and medical care. At the same time, Diabetes Mellitus (DM), type 1 (T1DM) and type 2 (T2DM), is increasing worldwide. READ MORE

  6. 14. Cardiovascular disease in patients with congenital heart disease

    Author : Maria Fedchenko; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Congenital heart disease; Myocardial infarction; Ischemic heart disease; Coarctation of the aorta; Cardiovascular risk factor;

    Abstract : Background: Today, about 95% of children with congenital heart disease (CHD) survive into adulthood and the survival in patients with CHD has increased considerably during the last decades. With increasing age, patients with CHD are at an increased risk of developing acquired cardiovascular disease, such as ischemic heart disease and myocardial infarction (MI). READ MORE

  7. 15. Socioeconomic status and cardiovascular vulnerability in women : psychosocial, behavioral and biological mediators

    Author : Sarah P Wamala; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Childhood circumstances; Coronary heart disease; Health behaviors; Hemostatic function; Lipids; Obesity; Physiological risk factors; Prognosis; Psychosocial stress; Socioeconomic status; Women;

    Abstract : Background: Cardiovascular disease (CVD) is the leading cause of death in both men and women in the industrialized world, and represents a major health and economic burden. Coronary heart disease (CHD), one of the most common of the cardiovascular diseases, is invariably more frequent in men and women of lower than higher socioeconomic status (SES). READ MORE