Search for dissertations about: "CLEAR CELL LESIONS"

Showing result 1 - 5 of 33 swedish dissertations containing the words CLEAR CELL LESIONS.

  2. 1. T-cell specificity and regulation in atherosclerosis

    Author : Anton Gisterå; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. READ MORE

  4. 2. Post-translational modifications in DNA base excision repair : The roles of CK2 and PARP-1

    Author : Cecilia Ström; Thomas Helleday; Hans Krokan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; base excision repair; single-strand break repair; PARP-1; CK2; XRCC1; mammalian cells; Cell and molecular biology; Cell- och molekylärbiologi; molekylärgenetik; Molecular Genetics;

    Abstract : Base lesions and DNA single-strand breaks (SSBs) are very common types of DNA damage. The base excision repair (BER) and single-strand break repair (SSBR) machineries both require a succession of enzymatic events in order to remove these types of endogenous lesions and to restore the DNA. READ MORE

  5. 3. Etiological and clinical studies of Langerhans cell histiocytosis (LCH)

    Author : Selma Olsson Åkefeldt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Langerhans cell histiocytosis (LCH) is a rare disease of unknown origin. LCH may occur at any age but affects mainly children and the most severe forms of the disease are seen in the youngest children. In LCH, granulomatous lesions are formed in various organs. READ MORE

  6. 4. Functional characteristics of periodontitis and peri-implantitis lesions in humans

    Author : Carlotta Dionigi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; periodontitis; peri-implantitis; biopsy; immunohistochemistry; oxidative stress; epigenetics; titanium micro-particles; proton-induced X-rays emission; RNA-sequencing; spatial transcriptomics;

    Abstract : In the current series of studies functional characteristics of periodontitis and peri-implantitis lesions in humans were investigated. Cell markers for antimicrobial activity were used to evaluate differences between periodontitis and peri-implantitis lesions (Study I), while epigenetic and oxidative stress markers were used to compare periodontitis lesions in smokers and non-smokers (Study II). READ MORE

  7. 5. Plasma cell malignancies in Sweden : subgroup descriptions and regional outcomes for multiple myeloma

    Author : Göran Wålinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Plasma cell disorders appear in various forms such as aggressive plasma cell leukemia (PCL), typical symptomatic multiple myeloma (MM), non-symptomatic smouldering multiple myeloma (SMM) and solitary plasmacytoma (SP). The different entities all require specific considerations regarding diagnosis and treatment. READ MORE