Search for dissertations about: "CNS"

Showing result 21 - 25 of 589 swedish dissertations containing the word CNS.

  2. 21. Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation

    Author : Cecilia Eriksson Linsmeier; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gtv-a; RCAS A -EGFP; transplantation; cell detection; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; GFP-actin; glial differentiation; neuronal differentiation; neurospheres; glial cultures; bFGF; EGF; cell expansion; cortical primordium; MGE; LGE; CNS; stem- progenitor cells;

    Abstract : In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols. READ MORE

  4. 22. Misfolded superoxide dismutase-1 in sporadic and familial Amyotrophic Lateral Sclerosis

    Author : Karin Forsberg; Thomas Brännström; Irina Alafuzoff; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD-1 motor neuron; protein misfolding; intranuclear; antibodies; CNS; brain; patologi; Pathology;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative syndrome of unknown etiology that most commonly affects people in middle and high age. The hallmark of ALS is a progressive and simultaneous loss of upper and lower motor neurons in the central nervous system that leads to a progressive muscle atrophy, paralysis and death usually by respiratory failure. READ MORE

  5. 23. Functions of platelet-derived growth factor-A during organogenesis

    Author : Linda Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor-A; knockout; mouse organogenesis; epithelial-mesenchymalinteractions; skin; hair follicles; CNS; lung; gastrointestinal villus;

    Abstract : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. READ MORE

  6. 24. Neural Interfaces to the Odour World of Scarab Beetles

    Author : Mattias Larsson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Djurekologi; Animal ecology; Intra; Antennal lobe; CNS; Attraction; Olfactometer; Behaviour; Mass spectrometry; Gas chromatography; Electrophysiology; Single sensillum; Receptor neuron; Plant volatile; Sex pheromone; Neuroethology; Odour detection; Olfaction; Coleoptera; Scarabaeidae; Entomology; plant parasitology; Entomologi; växtparasitologi; Environmental chemistry; Miljökemi;

    Abstract : Antennal detection and central nervous integration of behaviourally relevant odours in scarab beetles (Coleoptera: Scarabaeidae) was investigated, using the two Japanese scarabs Anomala cuprea and Phyllopertha diversa (Rutelinae), and the Central African fruit chafer Pachnoda marginata (Cetoniinae) as model species. Electrophysiological single cell recordings in A. READ MORE

  7. 25. EMBRYONIC GLIA AND FOREBRAIN NEUROGENESIS; in vitro generation and differentiation of telencephalic neurons

    Author : Charlotta Skogh; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta tubulin III; GFAP; RC2; Neurology; neuropsychology; neurofysiologi; DARPP-32; retinoic acid; serum; EGF; co-culture; cell culture; striatum; LGE; progenitor; precursor; radial glia; region specific; development; CNS; mouse; human; neurophysiology; Neurologi; neuropsykologi;

    Abstract : The current thesis is aimed to increase our understanding of the generation and differentiation of telencephalic neurons, with emphasis on the role of glial cells in these processes. Using in vitro methods we have studied the role of glial cells in neurogenesis, inheritance of genetic regional specification, and influence on differentiation of neurons. READ MORE