Search for dissertations about: "CNV"

Showing result 6 - 10 of 30 swedish dissertations containing the word CNV.

  2. 6. Methods and applications in DNA sequence alignments

    Author : Ellen Sherwood; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA sequence alignment; CNV; Chicken; Trypanosoma cruzi.;

    Abstract : DNA sequence alignment is one of the most common bioinformatics tasks. Alignment analysis for eukaryotic genomes is challenging because the datasets are large. Repeat sequences also make the analysis difficult. This thesis describes new methods which we have developed for DNA sequence alignment that address these problems. READ MORE

  4. 7. Matrix metalloproteinases and their inhibitors in ocular neovascularization

    Author : Björn Steén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angiogenesis; Neovascularization; Retina; Bruch membrane; Cornea; MMP; TIMP; VEGF; In situ hybridization.;

    Abstract : Growth of pathological new vessels (angiogenesis) in the eye is a leading cause of severe vision-loss. Ocular angiogenesis is seen in the anterior part of the eye as in corneal neovascularization, or in the posterior part as in diabetic retinopathy, retinopathy of prematurity or age-related macular degeneration. READ MORE

  5. 8. Sensorimotor function following anterior cruciate ligament injury : movement control, proprioception and neuropsychological perspectives

    Author : Adam Grinberg; Charlotte Häger; Martin Björklund; Dario G. Liebermann; Clare Ardern; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ACL; knee injury; sensorimotor control; proprioception; functional test; fear; anxiety; kinematics; electromyography; EMG; electroencephalography; EEG; brain; neuroplasticity; injury prevention; Sports Medicine; idrottsmedicin;

    Abstract : Background: The high incidence of anterior cruciate ligament (ACL) injuries in sports suggests an involvement of both biomechanical and neurocognitive risk factors. Athletes are constantly exposed to challenging sports scenarios, which are often characterised by high-intensity movements combined with a multi-stimuli environment and continuous psychological pressure. READ MORE

  6. 9. Genetic studies in mood disorders

    Author : Magnus Lekman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mood disorders, including bipolar disorder (BPD) and major depressive disorder (MDD), are highly complex psychiatric disorders. Decades of genetic studies have generated a large number of putative genetic susceptibility variants. However, with exception of CACNA1C, SYNE1 and ANK3 in BPD no robust association has as yet been identified. READ MORE

  7. 10. Transpupillary thermotherapy and photodynamic therapy for neovascular age-related macular degeneration

    Author : Anne Odergren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Age-related macular degeneration (AMD) is the leading cause of irreversible blindness among elderly in industrialized nations, and promises to extract an even greater toll with the imminent demographic shift. Neovascular AMD (wet AMD) often develops quickly and involves the growth of new blood vessels under the retina (choroidal neovascularization, CNV). READ MORE