Search for dissertations about: "CONFORMATIONAL STABILITY"

Showing result 1 - 5 of 64 swedish dissertations containing the words CONFORMATIONAL STABILITY.

  2. 1. Conformational Stability!? : Synthesis and Conformational Studies of Unnatural Backbone Modified Peptides

    Author : Anna S. Norgren; Per I. Arvidsson; Norbert Sewald; Uppsala universitet; []
    Keywords : Organic chemistry; Conformational investigations; β-peptides; glycosylation; biomolecular recognition; cyclic β³-peptides; cyclic mixed α β²-peptides; β-peptoids; Organisk kemi;

    Abstract : The beauty of the wide functionality of proteins and peptides in Nature is determined by their ability to adopt three-dimensional structures. This thesis describes artificial molecules developed to mimic secondary structures similar to those found crucial for biological activities. READ MORE

  4. 2. Autoproteolysis accelerated by conformational strain - a novel biochemical mechanism

    Author : Denny Johansson; Göteborgs universitet; []
    Keywords : SEA domain; autoproteolysis; MUC1; conformational strain; protein folding;

    Abstract : Natural fragmentation of polypeptide chains by autoproteolysis occurs in a number of protein families. It is a vital step in the maturation of several enzymes and in the formation of membrane-associated mucins that constitute a part of the protective mucus barrier lining epithelial cells. READ MORE

  5. 3. Molecular principles of protein stability and protein-protein interactions

    Author : Christofer Lendel; Per-Åke Nygren; Christopher M. Dobson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; binding thermodynamics; induced fit; molten globule; NMR spectroscopy; protein engineering; protein-protein interactions; protein stability; protein structure.; Structural biochemistry; Strukturbiokemi;

    Abstract : Proteins with highly specific binding properties constitute the basis for many important applications in biotechnology and medicine. Immunoglobulins have so far been the obvious choice but recent advances in protein engineering have provided several novel constructs that indeed challenge antibodies. READ MORE

  6. 4. Wood Hemicelluloses - Fundamental Insights on Biological and Technical Properties

    Author : Jennie Berglund; Mikael Lindström; Gunnar Henriksson; Francisco Vilaplana; Jakob Wohlert; Martin Lawoko; Maija Tenkanen; KTH; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; hemicellulose; wood; glucomannan; xylan; structure; acetylation; flexibility; solubility; interaction with cellulose; stability.; hemicellulosa; trä; glukomannan; xylan; struktur; acetylering; flexibilitet; löslighet; interaktion med cellulosa; stabilitet.; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Hemicelluloses are a group of heterogeneous polysaccharides representing around 30 % of wood where the dominating types are xylans, glucomannans and xyloglucans. Hemicelluloses complex molecular structure makes it difficult to understand the relationship between structure and properties entirely, and their biological role is not yet fully verified. READ MORE

  7. 5. Structural Studies of Binding Proteins: Investigations of Flexibility, Specificity and Stability

    Author : Ulrika Magnusson; Sherry L. Mowbray; Anthony J. Wikinson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Periplasmic binding protein; X-ray crystallography; conformational change; acidophile; protein specificity; protein structure; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Binding proteins are present both in gram-negative and gram-positive bacteria. They are the recognition components of the ABC transport systems that transport different nutrients into the cell, and are in some cases also involved in chemotaxis. READ MORE