Search for dissertations about: "COPI"

Showing result 1 - 5 of 8 swedish dissertations containing the word COPI.

  1. 1. Functional characterization of the secretory pathway and the role of COPI vesicles

    Author : Johan Hiding; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Golgi; Phosphoinositides; Fusion; COPI; ARF1; Proteomics; ER;

    Abstract : In the secretory pathway, proteins synthesized in the endoplasmatic reticulum move through the Golgi apparatus in a cis-to-trans direction and then sorts into different types of vesicles at the trans-Golgi network. How intracellular transport takes place has been the focus of cell biology research for a long time. READ MORE

  2. 2. The contribution of proteins and lipids to COPI vesicle formation and consumption

    Author : Fredrik Kartberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ARF1; COPI; ARFGAP; vesicle; fusion; diffusion;

    Abstract : In the secretory pathway, movement of proteins between compartments occurs through small (50-100 nm) vesicles. The coat of COPI vesicles is composed the small GTPase ARF1 and the large coatomer complex. In the secretory pathway, these vesicles mediate Golgi-to-ER and intra-Golgi transport. READ MORE

  3. 3. Vesicle transport in chloroplasts with emphasis on Rab proteins

    Author : Mohamed Alezzawi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : chloroplast; vesicle; transport; Arabidopsis; Rab; lipid; clathrin; protein; COPI; COPII;

    Abstract : Chloroplasts perform photosynthesis using PSI and PSII during its light-dependent phase. Inside the chloroplast there is a membrane called thylakoid. The thylakoid membranes are an internal system of interconnected membranes that carry out the light reactions of photosynthesis. READ MORE

  4. 4. The quality control of MHC class I antigen presentation

    Author : Kajsa M Paulsson; Antigen presentation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperone; assembly; COPI; antigenic peptide; TAP; MHC; tapasin; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). READ MORE

  5. 5. Mitotic Kinesin-Like Protein 1 (MKLP1/KIF23) in hereditary congenital dyserythropoietic anemia type III and in cancer

    Author : Ann-Louise Vikberg; Irina Golovleva; Monica Holmberg; Masanori Mishima; Pontus Aspenström; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Cell division; COPI; Congenital dyserythropoietic anemia; Cytokinesis; Gene expression; KIF23 protein human; Cancer; MKLP1 protein mouse; Mutation; medicinsk genetik; Medical Genetics;

    Abstract : A hereditary form of autosomal dominant congenital dyserythropoietic anaemiatype III (CDA III) has been reported in four families from Sweden, Argentina, Cuba and USA. CDA III patients might experience signs of mild anaemia and some of them need occasional blood transfusions. READ MORE