Search for dissertations about: "COX"

Showing result 21 - 25 of 487 swedish dissertations containing the word COX.

  2. 21. Involvement of Eicosanoid Signaling in Intestinal Epithelial Cell Survival

    Author : John Öhd; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; Tcf Lef; Bcl-2 family; b-catenin; 5-LO; apoptosis; cell survival; colorectal cancer; COX-2; LTD4; CysLT1 R; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Abstract : Eicosanoids are known to be involved in many different aspects of eukaryotic physiology and pathology. Notably, over the past 10 years much attention has been given to cyclooxygenase-2 (COX-2) due to its involvement in colorectal cancer. Less is known about the other major branch of arachidonic acid metabolism, namely the lipoxygenases (LO). READ MORE

  4. 22. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

    Author : Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

    Abstract : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. READ MORE

  5. 23. Kinins : important regulators in inflammation induced bone resorption

    Author : Anna Bernhold Brechter; Ulf Lerner; Hans-Erik Claesson; Umeå universitet; []
    Keywords : Bone resorption; Osteoblasts; Kinins; B1 and B2 receptors; IL-1β; TNF-α; Prostaglandin; COX-2; RANKL; Transcription factors; IL-4; IL-13; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Inflammatory processes in, or in close vicinity of, the skeleton often lead to loss of bone tissue. Different cytokines have been shown to be involved as stimulators of inflammatory induced osteoclastic bone resorption. READ MORE

  6. 24. Inhaled Nitric Oxide Therapy : Non-response and Rebound Response

    Author : Luni Chen; Eddie Weitzberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; nitric oxide inhalation; rebound response; non-response; endothelin-1; COX inhibitor; prostaglandin; ARDS; endotoxin; oleic acid; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård; Clinical Physiology; klinisk fysiologi;

    Abstract : Therapeutic inhaled nitric oxide (INO) has proved beneficial in patients with pulmonary hypertension. However, around 30-40% of the patients are non-responders to this therapy, and a life-threatening rebound response may occur during attempts to withdraw INO. READ MORE

  7. 25. Should I stay or should I go – Factors associated with hospitalization risk among older persons in Sweden

    Author : Jenny Hallgren; Anna K. Dahl Aslan; Eleonor Fransson; Marie Elf; Jönköping University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Older persons; hospitalization; risk factors; cognitive decline; qualitative content analyses; longitudinal; Cox regression; latent growth curve modelling;

    Abstract : An increasingly older population will most likely lead to greater demands on the health care system, as older age is associated with an increased risk of having acute and chronic conditions. The number of diseases or disabilities is not the only marker of the amount of health care utilized, as persons may seek hospitalization without a disease and/or illness that requires hospital healthcare. READ MORE