Search for dissertations about: "CPG"

Showing result 1 - 5 of 145 swedish dissertations containing the word CPG.

  2. 1. Arthritogenic property of bacterial DNA containing CpG motifs

    Author : Guo-Min Deng; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacterial DNA; CpG ODN; arthritis; macrophage; lymphocytes; TNFa; NF-kB; mice;

    Abstract : .... READ MORE

  4. 2. Crossing the Midline : Locomotor Neuronal Circuitry Formation

    Author : Fatima Memic; Klas Kullander; Avihu Klar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPG; CIN; neuronal network; locomotion; left-right alternation;

    Abstract : Networks at various levels of the nervous system coordinate different motor patterns such as respiration, eye or hand movements and locomotion. Intrinsic rhythm-generating networks that are located in the spinal cord generate motor behaviors that underlie locomotion in vertebrates. READ MORE

  5. 3. Computational modeling of the lamprey CPG : from subcellular to network level

    Author : Mikael Huss; Jeanette Hellgren Kotaleski; Anders Lansner; Ranu Jung; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Computer science; Datalogi;

    Abstract : Due to the staggering complexity of the nervous system, computer modelling is becoming one of the standard tools in the neuroscientist's toolkit. In this thesis, I use computer models on different levels of abstraction to compare hypotheses and seek un- derstanding about pattern-generating circuits (central pattern generators, or CPGs) in the lamprey spinal cord. READ MORE

  6. 4. The CpG island methylator phenotype in colorectal cancer : studies on risk and prognosis

    Author : Anna Dahlin; Richard Palmqvist; Bethany van Guelpen; Maria Henriksson; Åke Öberg; Xiao-Feng Sun; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; DNA methylation; folate; microsatellite instability MSI ; prognosis; risk factors; t-lymphocytes; the CpG island methylator phenotype CIMP ; Vitamin B12; Pathology; Patologi; Tumour biology; Tumörbiologi; patologi; Pathology;

    Abstract : Background Colorectal cancer (CRC) is the second most common malignancy in developed countries. The mortality is high, with nearly half of patients dying from the disease. The primary treatment of CRC is surgery, and decisions about additional treatment with chemotherapy are based mainly on tumor stage. READ MORE

  7. 5. Modulation of inflammation by immunostimulatory DNA

    Author : Jan Bjersing; Göteborgs universitet; []
    Keywords : CpG DNA; arthritis; phosphodiester; phosphorothioate; nucleotide modification; cytokines; chemokines; FcgammaR; B cell subsets.;

    Abstract : The aim of this thesis was to elucidate the roles of different types of DNA in inflammatory responses. We compared the immune responses to nuclease-protected phosphorothioate oligodeoxynucleotides (S-ODNs) and phosphodiester oligodeoxynucleotides (O-ODNs) that either contained or lacked CpG motifs. READ MORE