Search for dissertations about: "CR1"
Showing result 1 - 5 of 25 swedish dissertations containing the word CR1.
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1. Language Constructs for Safe Parallel Programming on Multi-Cores
Abstract : The last decade has seen the transition from single-core processors to multi-cores and many-cores. This move has by and large shifted the responsibility from chip manufacturers to programmers to keep up with ever-increasing expectations on performance. READ MORE
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2. Feedback Enhancement of Antibody Responses via Complement and Fc Receptors
Abstract : IgG, IgM and IgE in complex with antigen have the capacity to regulate specific immune responses. In this investigation, the role of Fc receptors for IgG (FcγRI, FcγRII and FcγRIII) and complement receptors 1 and 2 (CR1/2) for antibody-mediated enhancement of antibody responses are investigated. READ MORE
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3. The Role of IgM and Complement in Antibody Responses
Abstract : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. READ MORE
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4. IgM and Complement in Regulation of Antibody Responses
Abstract : Animals deficient in complement components C1q, C4, C3, and CR1/2 have severely impaired antibody responses. C1q is primarily activated by antibody-antigen complexes. Antigen-specific IgM in complex with an antigen is able to enhance the antibody response against that antigen. This is dependent on the ability of IgM to activate complement. READ MORE
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5. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis
Abstract : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms. However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. READ MORE