Search for dissertations about: "CXC"
Showing result 1 - 5 of 26 swedish dissertations containing the word CXC.
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1. On CXC Chemokines in Endotoxin-Induced Liver Injury
Abstract : Leukocyte recruitment is a rate-limiting step in endotoxemic liver injury. Leukocyte extravasation is a multistep process, supported by multiple combinations of adhesion molecules and chemokine receptors. This thesis examined the mechanisms of activation, adhesion and extravascular infiltration of leukocytes in endotoxin-induced liver injury. READ MORE
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2. On the cytotoxic and proinflammatory properties of eosinophils
Abstract : Eosinophils are multi-functional leukocytes involved in the pathophysiology of inflammatory diseases such as asthma and inflammatory bowel disease. Participation in some neoplastic diseases and in the host defense against helminths has also been postulated. They are considered both good and bad, protecting or harming the host. READ MORE
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3. On the role of mast cells in chemokine-induced leukocyte recruitment
Abstract : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. READ MORE
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4. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung
Abstract : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. READ MORE
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5. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury
Abstract : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. READ MORE