Search for dissertations about: "CXCL10"

Showing result 1 - 5 of 34 swedish dissertations containing the word CXCL10.

  1. 1. Immunological and Genetic Markers Predicting Treatment Outcome in Hepatitits C Virus Infection

    Author : Galia Askarieh; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : IP-10; CXCL10; CD26; hepatitis C virus; interferon; ribavirin; treatment; IL28B;

    Abstract : Hepatitis C is a blood-borne infection caused by the hepatitis C virus (HCV). A chronic infection, which develops in most infected subjects, may lead to liver cirrhosis with ensuing liver dysfunction and liver cancer. READ MORE

  2. 2. Natural killer cells in cancer : studies on migration and cytotoxicity

    Author : Erik Wennerberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : The role of natural killer (NK) cells in cancer development has been studied extensively over the last four decades and the increasing knowledge on NK cell regulation has improved both safety and efficacy of treatment. Despite these recent advances the clinical success has to date been modest in treatment of solid tumors, owing both to suboptimal directed migration of NK cells and the tumor cell’s resistance to NK cell-mediated lysis. READ MORE

  3. 3. Immune maturation and modulation in childhood allergies : Aspects of epigenetic, mucosal and systemic immune mediators in allergy development and prevention

    Author : Johanna Huoman; Maria Jenmalm; Lennart Nilsson; Petra Ina Pfefferle; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The prevalence of allergic diseases has in the past century increased among children in affluent societies. Underlying causes are incompletely disentangled, but decreased diversity in environmental and microbial exposures could drive allergy development. READ MORE

  4. 4. Assay development for studies of G protein-coupled receptors at the single-molecule level

    Author : Olov Wahlsten; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TIRF microscopy; colocalization; drug discovery; QCM-D; GPCR; pharmacodynamics; kinetics; equilibrium fluctuation analysis;

    Abstract : G protein-coupled receptors (GPCRs), also known as seven transmembrane (7TM) receptors,is the largest family of cell surface receptors. These receptors play a key role in transmittinga wide variety of signals across the cell membrane and are involved in physiologicalprocesses such as sensory transduction, cell-cell communication, neuronal transmission,and hormonal signaling. READ MORE

  5. 5. Type 1 diabetes : The autoimmune process and islet transplantation

    Author : Stella Jacobson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Type 1 diabetes (T1D) is an autoimmune disease characterized by the selective loss of the insulin-producing β-cells residing in the islets of Langerhans in the pancreas. Cytokines are involved in diabetes development in the nonobese diabetic (NOD) mouse model. READ MORE