Search for dissertations about: "CXI"

Showing result 1 - 5 of 10 swedish dissertations containing the word CXI.

  2. 1. Cartilage proteins and their arthritogenic properties in arthritis

    Author : Stefan Carlsén; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; Immunology; HLA-DR4; tolerance; COMP; CXI; CIX; arthritis; Cartilage; collagen;

    Abstract : In this thesis the role of cartilage proteins and their potential as antigen and availability to the immune system in arthritis were investigated. Six papers are included; where four present new animal models for Rheumatoid arthritis (RA), one shows how genetic disorders in cartilage may affect arthritis and the last how posttranslational modification of collagen type II (CII) affects tolerance. READ MORE

  4. 2. Statistical processing of Flash X-ray Imaging of protein complexes

    Author : Alberto Pietrini; Carl Nettelblad; Johan Bielecki; Janos Hajdu; Flavio Capotondi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray; XFEL; single particle; hit-finder; statistical hit-finder; single protein; protein complex; RNA polymerase II; FEL; free-electron laser; FXI; Flash X-ray Imaging; CXI; CSPAD; x-ray imaging; COACS; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Flash X-ray Imaging (FXI) at X-ray Free Electron Lasers (XFELs) is a promising technique that permits the investigation of the 3D structure of molecules without the need for crystallization, by diffracting on single individual sample particles.In the past few years, some success has been achieved by using FXI on quite large biological complexes (40 nm-1 μm in diameter size). READ MORE

  5. 3. Algorithms for Coherent Diffractive Imaging with X-ray Lasers

    Author : Benedikt J. Daurer; Filipe Maia; Tomas Ekeberg; Janos Hajdu; Richard Neutze; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray lasers; coherent diffractive imaging; algorithms; lensless imaging; flash diffractive imaging; flash X-ray imaging; aerosol injection; FEL; XFEL; CXI; CDI; FXI; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Coherent diffractive imaging (CDI) has become a very popular technique over the past two decades. CDI is a "lensless" imaging method which replaces the objective lens of a conventional microscope by a computational image reconstruction procedure. READ MORE

  6. 4. Flash Diffractive Imaging in Three Dimensions

    Author : Tomas Ekeberg; Janos Hajdu; Keith Nugent; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray; diffraction; mimivirus; three dimensional; phase retrieval; EMC; manifold embedding; CXI; FEL; free-electron laser; single particle; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : During the last years we have seen the birth of free-electron lasers, a new type of light source ten billion times brighter than syncrotrons and able to produce pulses only a few femtoseconds long. One of the main motivations for building these multi-million dollar machines was the prospect of imaging biological samples such as proteins and viruses in 3D without the need for crystallization or staining. READ MORE

  7. 5. Coherent Diffractive Imaging with X-ray Lasers

    Author : Max Felix Hantke; Filipe R. N. C. Maia; Janos Hajdu; Martin Svenda; Edgar Weckert; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; coherent diffractive X-ray imaging; lensless imaging; coherent X-ray diffractive imaging; flash diffractive imaging; single particle imaging; aerosol injection; electrospray injection; substrate-free sample delivery; carboxysome; phase retrieval; X-ray diffraction software; X-ray free-electron laser; XFEL; FEL; CXI; CDI; CXDI; FXI;

    Abstract : The newly emerging technology of X-ray free-electron lasers (XFELs) has the potential to revolutionise molecular imaging. XFELs generate very intense X-ray pulses and predictions suggest that they may be used for structure determination to atomic resolution even for single molecules. READ MORE