Search for dissertations about: "CYP2D6"
Showing result 1 - 5 of 45 swedish dissertations containing the word CYP2D6.
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1. Pharmacogenetic analysis in sickness and in health - for better or for worse
Abstract : An individual's pharmacogenetic constitution may predict response to drugs, hormones and toxins, and might be a susceptibility factor for disease. Pharmacogenetic diversity is especially pronounced for drug metabolising enzymes. READ MORE
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2. Clinical Aspects of Depression in Psychiatric Care
Abstract : .... READ MORE
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3. Migraine in women : Epidemiological, clinical, genetic, and experimental aspects
Abstract : Migraine is a significant public-health problem. Few studies have focused on migraine inmiddle-aged and older women in the general population. READ MORE
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4. First-pass Intestinal Metabolism of Drugs : Experiences from in vitro, in vivo and simulation studies
Abstract : The bioavailability of a drug can be described as the fraction of an orally administered dose that reaches the systemic circulation and is often limited by first-pass metabolism in the gut and the liver. It is important to have knowledge about these processes since the systemic blood drug concentration is tightly connected to the effect of the drug. READ MORE
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5. Pharmacogenetics from a Forensic Perspective : CYP2D6 and CYP2C19 genotype distributions in autopsy cases
Abstract : In Sweden about 550 individuals die every year due to drug intoxication. A challenge for the forensic toxicologist is to determine whether or not the analytical results can explain intoxication as a cause of death. The most common drugs found among intoxication cases are psychiatric drugs and analgesics. READ MORE