Search for dissertations about: "Ca oscillations"

Showing result 1 - 5 of 14 swedish dissertations containing the words Ca oscillations.

  2. 1. Regulation of spontaneous tone in guinea pig trachea

    Author : Staffan Skogvall; Neurofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; lidocaine; substance P; tachykinin; prostaglandin; indomethacin; capsaicin; neuroepithelial endocrine cells; epithelium; oxygen; oscillations; spontaneous tone; Asthma; airway smooth muscle; electrical field stimulation.; Physiology; Fysiologi;

    Abstract : Asthma is a common disease, characterized by periods of bronchoconstriction of unclear origin. This thesis examines a specific behavior of airway smooth muscle, the so-called spontaneous airway tone. It was suspected that a defect regulation of this tone may be a cause of asthmatic bronchoconstriction. READ MORE

  4. 2. Pitfalls in β-cell ion imaging with fluorescent indicators and their use for real-time detection of somatostatin secretion

    Author : Mingyu Yang; Anders Tengholm; Enming Zhang; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-cells; cytoplasmic Ca²⁺; cytoplasmic pH; fluorescent indicators; pancreatic islets; R-GECO1; somatostatin; type 2 diabetes; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Fluorescent ion indicators have become indispensable tools in cell physiology. Dye indicators can easily be loaded into most types of cells, while genetically encoded indicators are advantageous in allowing specific cellular or subcellular targeting. READ MORE

  5. 3. Temporal monitoring of intracellular Ca2+ signaling and origins of Ca2+ oscillations

    Author : Dominic-Luc Webb; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis examined parameters influencing stimulated cytoplasmic free Ca2+ concentration ([Ca2+]i) oscillations in hepatocytes and pancreatic beta-cells. Hepatic glucose output is regulated in part by hormones such as vasopressin that act through [Ca 2+]i oscillations. READ MORE

  6. 4. Studies of SNAP-25 in regulated membrane fusion : metabolic consequences and tuning of intracellular Ca(2+) dynamics in beta cells

    Author : Teresa Daraio; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Increased release of insulin is usually regarded as a symptom of metabolic syndrome, contributing to insulin resistance in peripheral organs thus affecting glucose and insulin homeostasis. The existing animal models to address the metabolic syndrome are currently not optimal. READ MORE

  7. 5. Patch clamp and calcium studies on human colonic mucosal cells

    Author : Peter Sand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human; colon crypt; HT29; K channel; Ca oscillations; volume regulation; patch clamp;

    Abstract : Background: The main function of the large intestine is to fine-tune electrolyte and water balance. This is achieved through the consorted action of ion channels, transporters and pumps. Failures of this system can lead to diarrhoea. READ MORE