Search for dissertations about: "Caco-2 cells"

Showing result 21 - 25 of 51 swedish dissertations containing the words Caco-2 cells.

  1. 21. Bioactivity of Medicinal Bolivian Andean plants. Effects on cell proliferation and related processes

    Author : Gloria Rodrigo; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bolivian medicinal plants; colon cancer; cell proliferation; DNA synthesis; apoptosis; caspase-3; sesquiterpene; curcuphenol; damsin; coronopilin;

    Abstract : Colon cancer is common in both developed and developing countries, and is responsible for at least 600,000 deaths globally every year. It is therefore the second most common cause of cancer-related mortality. Extensive studies are being conducted worldwide to find more effective drugs that can be used in cancer treatment. READ MORE

  2. 22. The mucus layer and other barriers to intestinal drug absorption

    Author : Agneta Wikman Larhed; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : The extraepithelial mucus layer acts as a barrier to the absorption and diffusion of drugs. Three in vitro models have been used for studies of this and other intestinal barriers to drug transport. A drug absorption model based on monolayers of the mucus-producing human intestinal goblet HT29-H cell line was developed. READ MORE

  3. 23. Dietary fatty acids increase the absorption of toxic substances and drugs by modifying different absorption pathways in the intestinal epithelium

    Author : Bitte Aspenström-Fagerlund; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Dietary fatty acids have surface active properties comparable to substances used as absorption enhancers of poorly absorbed drugs. The intestinal epithelium serves as a gatekeeping barrier for the absorption of toxic substances, nutrients and drugs. READ MORE

  4. 24. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development

    Author : Sofia Gustafsson; Stig Jacobsson; Birgitta Sander; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cannabinoids; cell viability; neuronal differentiation; colorectal cancer; chick embryo; biokemisk farmakologi; biochemical pharmacology; Toxicology; toxikologi;

    Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE

  5. 25. Biological Activities of Natural and Semi-Synthetic Pseudo-Guaianolides: Inhibition of Transcription Factors

    Author : Rodrigo Villagomez; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pseudo-guaianolides; sesquiterpene lactones; NF-κB;

    Abstract : Damsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. READ MORE