Search for dissertations about: "Calcium oscillations"

Showing result 11 - 15 of 35 swedish dissertations containing the words Calcium oscillations.

  2. 11. Calcium signaling : molecular mechanisms and cellular consequences

    Author : Seth Malmersjö; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells exploit calcium (Ca2+) signaling to transmit information. In a multicellular organism, each cell must be able recognize, process, and respond to information received from the surrounding environment. In this thesis I investigate molecular mechanisms and cellular consequences of Ca2+ signaling. READ MORE

  4. 12. Oxidative stress and calcium signalling : implications for diabetes and cardiac glycosides

    Author : Mark Lal; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Calcium; diabetes; Na; K-ATPase; ouabain; oxidative stress;

    Abstract : The signal transduction processes by which an individual cell is able to recognize and respond to its external environment are critical to determining its survival as well as that of the entire organism. In the current study we have investigated the intracellular signalling cascades activated downstream of two separate stimuli: the diabetic milieu and the cardiac glycoside, ouabain. READ MORE

  5. 13. Patch clamp and calcium studies on human colonic mucosal cells

    Author : Peter Sand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human; colon crypt; HT29; K channel; Ca oscillations; volume regulation; patch clamp;

    Abstract : Background: The main function of the large intestine is to fine-tune electrolyte and water balance. This is achieved through the consorted action of ion channels, transporters and pumps. Failures of this system can lead to diarrhoea. READ MORE

  6. 14. Calcium signaling and network activity : mathematical modeling and molecular mechanisms

    Author : Erik Smedler; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The calcium (Ca2+) ion is a versatile second messenger present in all cells. It is involved in such diverse processes as cell division, differentiation, vesicle transport and muscle contraction. Its widespread applicability is partially explained by its wide temporal and spatial dynamics. READ MORE

  7. 15. Effects of bacterial toxins on calcium homeostasis in renal inflammation

    Author : Tomas Söderblom; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Calcium (Ca2+) is a highly versatile ion used for intra- and inter-cellular signalling in eukaryotic cells, and numerous cellular events are regulated by alteration of the intracellular Ca2+ concentration. We hypothesized that bacterial virulence factors may alter the Ca 2+ homeostasis in epithelial cells such that the innate immune response is affected. READ MORE