Search for dissertations about: "Calpain-10"
Found 5 swedish dissertations containing the word Calpain-10.
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1. Genetic studies of diabetes in northern Sweden
Abstract : Diabetes mellitus represents a group of metabolic disorders caused by both environmental and genetic factors. The two most common forms of diabetes are type 2 diabetes (T2D) and type 1 diabetes (T1D). T2D is associated with obesity and the disease is caused by insulin resistance and pancreatic b-cell dysfunction. READ MORE
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2. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity
Abstract : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. READ MORE
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3. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes
Abstract : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. READ MORE
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4. Mapping genetic diseases in northern Sweden
Abstract : The population of northern Sweden has previously been shown to be well suited for the mapping of monogenic diseases. In this thesis we have tested the hypothesis that this population could also be used for efficient identification of risk genes for common diseases. READ MORE
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5. Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes
Abstract : Diabetes mellitus is a common multifactorial disease that needs lifelong treatment of insulin and/or oral treatment to prevent hyperglycaemia. Despite treatment, patients with diabetes, still suffer from severe complications later in life. READ MORE