Search for dissertations about: "Calreticulin CRT"

Showing result 1 - 5 of 8 swedish dissertations containing the words Calreticulin CRT.

  2. 1. Plant Calreticulins -Calcium-binding proteins with many functions

    Author : Anna Christensen; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tobacco; plant; calreticulin; isoforms; Arabidopsis; localization; mouse embryonic fibroblasts;

    Abstract : Endoplasmic reticulum (ER) plays an important role in protein synthesis, folding, maturation and transport of newly synthesized proteins, as well as the regulation of cellular Ca2+ homeostasis. A protein that is involved in several of these functions in the ER is calreticulin (CRT), which is a Ca2+-binding chaperone that resides in the lumen of the ER. READ MORE

  4. 2. Mechanisms involved in macrophage phagocytosis of apoptotic cells

    Author : Anna Nilsson; Per-Arne Oldenborg; Karl-Eric Magnusson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; macrophages; dendritic cells; phagocytosis; apoptotic cells; senescent erythrocytes; CD47; SIRPalpha; LRP1; calreticulin; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. READ MORE

  5. 3. Studies on three matrix molecules in bone and dentin

    Author : Ulrika Petersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Osteoadherin OSAD ; Nucleobindin Nuc ; Calreticulin CRT ; biomineralization; osteogenesis; dentinogenesis;

    Abstract : The biomineralization of bone and dentin is a complex and dynamic process, involving the formation of an organic framework in which mineral crystals are deposited. The noncollagenous proteins (NCPs) of the organic phase play a central role in the extracellular matrix (ECM) organization and mineralization regulation. READ MORE

  6. 4. Novel non-collagenous modulators of biomineralization in bone and dentin

    Author : Eszter Somogyi-Ganss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Calreticulin; nucleobindin; prothrombin; biomineralization; osteogenesis; dentinogenesis;

    Abstract : The formation of mineralized tissues such as bones and teeth is governed on many levels by molecular, genetic, and cellular events to culminate in terminally differentiated cells that secrete a specialized organic matrix, which is later mineralized through the coordinated deposition of calcium phosphate crystals. The formation of this hard tissue phase is tightly regulated by components of the extracellular matrix (ECM), since deviations from this equilibrium result in prevalent, debilitating health problems such as arthritis, vascular calcification, periodontal disease and osteoporosis. READ MORE

  7. 5. Plant Calreticulins - isoforms, localization and function

    Author : Karin Svensson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; arabidopsis thaliana; calcium; isoform; endoplasmic reticulum; chaperone; tunicamycin;

    Abstract : Calreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. READ MORE