Search for dissertations about: "Capsular polysaccharide"

Showing result 1 - 5 of 38 swedish dissertations containing the words Capsular polysaccharide.

  2. 1. Detection of polysaccharides and polysaccharide antibodies in pneumococcal pneumonia

    Author : Simon Athlin; Kristoffer Strålin; Hans-Christian Slotved; Hans Fredlund; Kristian Riesbeck; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pneumoniae; pneumococcus; pneumonia; cellwall polysaccharide; capsular polysaccharide; antibody urinary antigen; nasopharyngeal aspirate; antibody; immunoglobulin; adult; Medicine; Medicin;

    Abstract : .... READ MORE

  4. 2. Synthesis of Structures Related to the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and to Mycothiol

    Author : Rikard Slättegård; Stefan Oscarson; Andrei Nikolaev; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; Capsular polysaccharide; Mycobacterium tuberculosis; Mycothiol; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : This thesis describes the synthesis of structures related to the capsular polysaccharide of Neisseria meningitidis serogroup A and the synthesis of analogues of mycothiol, a compound produced by Mycobacterium tuberculosis. The first part of the thesis describes the synthesis of structural elements present in the native capsular polysaccharide of Neisseria meningitidis serogroup A. READ MORE

  5. 3. Development of strategies for construction of thioglycoside building blocks corresponding to repeating triads of Cryptococcus neoformans GXM capsular polysaccharide

    Author : Lina Rydner; Stefan Oscarson; Olof Ramström; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crytococcus neoformans; Capsular polysaccharide; Thioglycosides; Convergent synthesis; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis focuses on the development of methods for synthesis of thioglycoside building blocks corresponding to the repeating units of the capsular polysaccharide (CPS) of Cryptococcus neoformans, an opportunistic fungal pathogen. The building blocks are suitable for construction of large synthetic oligosaccharides related to the native CPS-structures which are to be used in biological studies in order to identify protective epitopes with the aim to develop a glycoconjugate vaccine against C. READ MORE

  6. 4. Synthesis of oligosaccharides related to the capsular polysaccharide of Neisseria meningitidis serotype A

    Author : Peter Teodorovic; Stefan Oscarson; Mikael Elofsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Abstract : In order to find suitable stable vaccine candidates against Neisseria meningitidis group A, several structures related to the capsular polysaccharide have been synthesised. The first part of the thesis describes the synthesis of C-phosphonate analogues starting from glucose. READ MORE

  7. 5. Structural studies of two bacterial polysaccharide antigens : synthesis and chemical modification of low molecular weight carbohydrates

    Author : Carmen Ortega; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The structures of two bacterial antigens, one a capsular polysaccharide from Klebsiella K66 and the other a lipopolysaccharide from Escherichia coli 0:6, have been determined, using specific degradations and spectrochemical studies. Two glycosidation methods are described. READ MORE