Search for dissertations about: "Carbapenem"
Showing result 1 - 5 of 16 swedish dissertations containing the word Carbapenem.
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1. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli
Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE
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2. Carbapenem resistance in Pseudomonas aeruginosa
Abstract : Carbapenem (imipenem and meropenem) resistance in Pseudomonas aeruginosa is increasing, with global resistance rates approaching 20%. The most common resistance mechanisms are down-regulation of the porin OprD, and increased activity of multi-drug efflux pumps, primarily MexAB-OprM. READ MORE
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3. Synthetic studies on carbapenem antibiotics and the alkaloid (+)-nitramine
Abstract : .... READ MORE
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4. The antimicrobial role of human MAIT cells
Abstract : MAIT cells are unconventional T cells that have characteristics of both innate and adaptive immunity. Their fast mobilization and wide distribution in tissues make them part of the first line of defense against infection. MAIT cells recognize riboflavin-related metabolites produced by bacteria and presented by MR1. READ MORE
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5. Studies on the molecular mechanisms of resistance to fluoroquinolones and carbapenems in selected bacterial species
Abstract : The emergence of mutant bacteria with multi-resistant phenotype, no longer responsive to any of the available therapeutic agents is a growing concern. We have investigated the resistance mechanisms to two classes of antibacterials with broad spectrum of activity, carbapenems and fluoroquinolones. READ MORE