Search for dissertations about: "Cardiology biomarkers"

Showing result 1 - 5 of 17 swedish dissertations containing the words Cardiology biomarkers.

  1. 1. Platelet Inhibition, Revascularization, and Risk Prediction in Non-ST-elevation Acute Coronary Syndromes

    Author : Daniel Lindholm; Stefan James; Christoph Varenhorst; James de Lemos; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndrome; non-ST-elevation acute coronary syndrome; P2Y12 inhibitors; ticagrelor; biomarkers; revascularization; percutaneous coronary intervention; risk prediction; Cardiology; Kardiologi;

    Abstract : Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most common manifestation. Despite improved outcomes during the last decades, patients with acute coronary syndromes (ACS) are still at substantial risk of recurrent ischemic events and mortality. READ MORE

  2. 2. Biomarkers of Renal Function in Acute Coronary Syndromes

    Author : Axel Åkerblom; Stefan James; Lars Wallentin; Torbjörn Omland; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystatin C; glomerular filtration rate; GFR; creatinine; acute coronary syndrome; ACS; kidney; renal; mortality; death; myocardial infarction; Cardiology; Kardiologi; Medicin; Medicine; Internal Medicine; Internmedicin;

    Abstract : The thesis aimed to investigate cystatin C and creatinine-based estimates of glomerular filtration rate (eGFR), both at admission and during follow-up, on the combined endpoint of cardiovascular death and myocardial infarction in patients with acute coronary syndrome (ACS). We also evaluated two cystatin C assays and assessed genetic determinants of cystatin C concentrations. READ MORE

  3. 3. New Risk Markers in Atrial Fibrillation

    Author : Ziad Hijazi; Jonas Oldgren; Lars Wallentin; Agneta Siegbahn; Ola Hammarsten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; stroke risk; cardiac biomarkers; troponin; natriuretic peptides; NT-proBNP; risk stratification; Cardiology; Kardiologi;

    Abstract : Atrial fibrillation (AF) confers an independent increased risk of stroke and death. The stroke risk is very heterogeneous and current risk stratification models based on clinical variables, such as the CHADS2 and CHA2DS2VASc score, only offer a modest discriminating value. READ MORE

  4. 4. Importance of peripheral arterial disease as a risk marker in patients with myocardial infarction

    Author : Birgitta Jönelid; Christina Christersson; Nina Johnston; Bertil Lindahl; Bertil Andrén; Lena Jonasson; Uppsala universitet; []
    Keywords : Coronary heart disease; Peripheral artery disease; Polyvascular disease; Inflammatory biomarkers; TNFR-1; TNFR-2; GDF-15; Cardiovascular events.; Cardiology; Kardiologi;

    Abstract : The purpose of this thesis was to describe the true prevalence of widespread arterial disease in a cohort with patients with a recent myocardial infarction (MI) to find valuable clinical methods to detect these patients. Our aim was also to investigate biomarker relationships with peripheral artery disease (PAD) and the importance of PAD in patients’ long-term outcomes. READ MORE

  5. 5. Emerging biomarkers in cardiometabolic disease

    Author : John Molvin; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes mellitus; type 2; Biomarker discovery; Cardiometabolic disease; cardiometabolic biomarkers; CVD; galectin 4; Olink;

    Abstract : AbstractThe epidemiological association between diabetes and heart failure is well-established and the two entities areemerging as global threats, both individually and synergistically, to an aging population. The exploration of multipleproteins can shed light on pathophysiological pathways in both diabetes and cardiovascular disease. READ MORE