Search for dissertations about: "Cardioprotective treatment strategies"
Showing result 1 - 5 of 6 swedish dissertations containing the words Cardioprotective treatment strategies.
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1. Cardioprotective treatment strategies
Abstract : In myocardial ischemia-reperfusion (I/R) injury, complement activation, tissue plasminogen activator (t-PA) and extracellular adenosine triphosphate (ATP) release contribute to myocardial injury. ATP is degraded into adenosine by the enzyme apyrase, and adenosine possesses cardioprotective properties. READ MORE
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2. PGE2 and other lipids in rheumatic diseases
Abstract : Despite numerous options for treatment of rheumatic diseases, there is an unfulfilled clinical need for therapeutic strategies that can reduce inflammation and prevent tissue destruction. Lipid mediators (eicosanoids and fatty acids (FA)) are involved in the regulation of inflammatory processes and contribute to the pathogenesis of rheumatic diseases. READ MORE
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3. Epigenetic influence on cardiovascular protective mechanisms in vivo: explorations of t-PA release and extracellular vesicle genetic content
Abstract : ABSTRACT Background: Ischemic heart disease is one of the leading causes of death globally. This thesis explores endogenous mechanisms protecting against myocardial ischemia in context of epigenetics (changes in gene activity not caused by changes in DNA sequences). READ MORE
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4. Studies on Cell Injury Induced by Hypoxia-Reoxygenation and Oxidized Low Density Lipoprotein : With Special Reference to the Protectiove Effect of Mixed Tocopherols, Omega-3 Fatty Acids and Transforming Growth Factor-beta1
Abstract : Hypoxia-reoxygenation (H-R) injury is an important clinical phenomenon in patients with coronary artery disease (CAD). Endothelial injury is a critical step in the initiation and progression of atherosclerosis. Therefore, endothelial and cardiomyocyte protection has been considered an effective step in prevention and treatment of CAD. READ MORE
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5. Quantitative and Qualitative Assessment of the Myocardium at Risk
Abstract : One of the major determinants of the final infarct size during an acute coronary occlusion is the size of the myocardium subjected to ischemia. Identification and quantification of this so-called myocardium at risk in the acute phase of ischemia has been difficult in patients with conventional methods, such as myocardial perfusion single-photon emission computed tomography (SPECT) or electrocardiography. READ MORE